28 products were found matching "K22599"!

Ritonavir is an HIV protease inhibitor. It inhibits recombinant HIV-1 protease by 79% when used at a concentration of 0.5 nM. It inhibits HIV-13B-induced cell death in MT-4 human T cell leukemia cells (EC50 = 25 nM) as well as cell death induced by HIV-1LAI, HIV-2ROD, and HIV-2EHO in human MT-2 cells (IC50s = 0.045,...

Saquinavir is an HIV protease inhibitor (Kis = 0.12 and 50 = 2 nM). It also inhibits the activity of the severe acute respiratory coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro), with an IC50 value of 9.92 µM.Formal Name:...

Tipranavir is a potent, orally bioavailable nonpeptidic HIV aspartyl protease inhibitor (Ki = 95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Chloroform: slightly soluble, Methanol: slightly soluble. lambdamax: 254 nm. SMILES:...

Soluble in DMSO (15mg/ml), DMF (20mg/ml) or ethanol (20mg/ml). Nelfinavir is an orally bioavailable competitive inhibitor of the human immunodeficiency virus. It potently inhibits HIV-1 (Ki=2nM) and HIV-2 protease in vitro. HIV-1 protease is important for the replication of the virus within the cell and the release...

Soluble in DMSO (10mg/ml). Saquinavir is an antiretroviral inhibitor of the human immunodeficiency virus. It potently inhibits HIV-1 (Ki=0.12nM) and HIV-2 (Ki<0.1nM) protease in vitro. HIV-1 protease is important for the replication of the virus within the cell and the release of mature viral particles from the...

Description: Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM. Target: SARS-CoV, HIV Protease. Smiles: OS(O)(=O)=O.CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12....

Fosamprenavir is a prodrug form of the HIV-1 protease inhibitor amprenavir (Cay-15369). It is converted to amprenavir by alkaline phosphatase in the intestinal epithelium. Formulations containing fosamprenavir have been used in the treatment of HIV infections.Formal Name:...

Atazanavir metabolite, HIV protease inhibitor.

Saquinavir-d9 is intended for use as an internal standard for the quantification of saquinavir (Cay-9001893) by GC- or LC-MS. Saquinavir is an HIV protease inhibitor (Kis = 0.12 and 50 = 2 nM). It also inhibits the activity of the severe acute respiratory coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known...

Tipranavir-d4 is intended for use as an internal standard for the quantification of tipranavir (Cay-21028) by GC- or LC-MS. Tipranavir is a potent, orally bioavailable nonpeptidic HIV aspartyl protease inhibitor (Ki = 99% deuterated forms (d1-d4). Formulation: (Request formulation change), A solid. Solubility:...

Soluble in DMSO (30mg/ml) or DMF (30mg/ml). Darunavir is a highly potent HIV protease inhibitor (IC50=3-6nM, depending on laboratory HIV-1 strain), an antiretroviral medication used to treat and prevent HIV/AIDS. Darunavir is a second generation HIV-1 protease inhibitor that inhibits replication of various...

Soluble in ethanol (20mg/ml), DMSO (15mg/ml) or dimtheylformamide (15mg/ml). The antiviral agent Lopinavir is a potent inhibitor of HIV-1 protease (Ki=1.3pM for wild-type enzyme) and has been shown to block the replication of clinical isolates of HIV (EC50s=5-52nM). Lopinavir is an antiretroviral of the protease...