35 products were found matching "K22184"!
No results were found for the filter!
NEW
FHD-609
Item number: Cay46304-1
FHD-609 is a proteolysis-targeting chimera (PROTAC) and derivative of dBRD9 (Cay-45720). It degrades bromodomain-containing protein 9 (BRD9) in SYO-1 synovial sarcoma cells.. SMILES: COC(C=C(C(C1=CC(N2CCC2)=NC=C13)=CN(C)C3=O)C=C4OC)=C4CN5CCC(CN6CCC7(CC6)CN(C7)C8=CC=C9CN(C(C9=C8)=O)[C@@H]%10C(NC(CC%10)=O)=O)CC5....
| Keywords: | (3S)-3-[6-[7-[[1-[[4-[6-(1-azetidinyl)-1,2-dihydro-2-methyl-1-oxo-2,7-naphthyridin-4-yl]-2,6-dimethoxyphenyl]methyl]-4-pip... |
| Application: | BRD9 degradation driving PROTAC |
| CAS | 2676211-64-4 |
| MW: | 829.01 D |
From 49.00€
*
dBRD9
Item number: Cay45720-1
dBRD9 is a proteolysis-targeting chimera (PROTAC) composed of a bromodomain-containing protein 9 (BRD9) inhibitor conjugated to the cereblon (CRBN) inhibitor pomalidomide (Cay-19877) via an alkyl ether linker. It selectively degrades BRD9 over BRD4 and BRD7 at 100 nM and reduces the proliferation of MOLM-13 leukemia...
| Keywords: | 2-[[[4-(1,2-dihydro-2-methyl-1-oxo-2,7-naphthyridin-4-yl)-2,6-dimethoxyphenyl]methyl]methylamino]-N-[2-[2-[2-[[2-(2,6-diox... |
| Application: | BRD9 degradation driving PROTAC |
| CAS | 2170679-45-3 |
| MW: | 783.84 D |
From 153.00€
*
Anti-BRD9
Item number: A303-781A
Protein function: May play a role in chromatin remodeling and regulation of transcription. [The UniProt Consortium]
| Keywords: | Anti-BRD9, Anti-Bromodomain-containing protein 9, Anti-Rhabdomyosarcoma antigen MU-RMS-40.8 |
| Application: | WB, IP |
| Host: | Rabbit |
| Species reactivity: | human |
From 165.00€
*
BRD9 (135-242), His-tag, human recombinant protein
Item number: BPS-31090
Human Bromodomain containing 9, also known as BRD9, amino-acids 135-242 (GenBank Accession No. NM_023924) with N-terminal HIS tag, MW = 13.4 kDa, expressed in an E. coli expression system.
| Keywords: | BRD9, Bromodomain-containing protein 9, Rhabdomyosarcoma antigen MU-RMS-40.8, |
| Application: | Binding assays, inhibitor screening, selectivity profiling |
| MW: | 13.4 kD |
461.00€
*
I-BRD9
Item number: TGM-T6859-5mg
Description: I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3. Target: Epigenetic Reader Domain. Smiles: CCn1cc(-c2cccc(c2)C(F)(F)F)c2sc(cc2c1=O)C(=N)NC1CCS(=O)(=O)CC1. References: Theodoulou NH, et al. J Med Chem. 2016, 59(4):1425-1439.
| Keywords: | GSK602 |
| Application: | BRD9 bromodomain inhibitor |
| CAS | 1714146-59-4 |
| MW: | 497.55 D |
From 33.00€
*
BRD9 (135-242), human recombinant protein, GST-tag
Item number: BPS-31091
Human Bromodomain containing 9, also known as BRD9, amino-acids 135 ? 242 (GenBank Accession No. NM_023924) with N-terminal GST tag, MW = 39 kDa, expressed in an E. coli expression system.
| Keywords: | BRD9, Bromodomain-containing protein 9, Rhabdomyosarcoma antigen MU-RMS-40.8, |
| Application: | Binding assays, screening inhibitors, selectivity profiling |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 39 kD |
461.00€
*
BRD9 TR-FRET Assay Kit
Item number: BPS-32621
The BRD9 TR-FRET Assay Kit is designed to measure the inhibition of BRD9 binding to its substrate in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and...
| Keywords: | Bromodomain containing 9, BRD9, BRD-9, |
| Application: | Inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
804.00€
*
Anti-BRD9
Item number: E-AB-18545.120
May play a role in chromatin remodeling and regulation of transcription. Protein function: Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or...
| Keywords: | Anti-BRD9, Anti-Bromodomain-containing protein 9, Anti-Rhabdomyosarcoma antigen MU-RMS-40.8, BRD9 Polyclonal Antibody |
| Application: | WB, IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 89.00€
*
Anti-BRD9
Item number: E-AB-52478.120
May play a role in chromatin remodeling and regulation of transcription. Protein function: Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or...
| Keywords: | Anti-BRD9, Anti-Bromodomain-containing protein 9, Anti-Rhabdomyosarcoma antigen MU-RMS-40.8, BRD9 Polyclonal Antibody |
| Application: | WB, IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 89.00€
*
Anti-BRD9
Item number: ATA-HPA021465.100
Protein function: Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797). Component of SWI/SNF chromatin remodeling...
| Keywords: | Anti-BRD9, Anti-Bromodomain-containing protein 9, Anti-Rhabdomyosarcoma antigen MU-RMS-40.8 |
| Application: | WB, ICC |
| Host: | Rabbit |
| Species reactivity: | human |
From 246.00€
*
Anti-BRD9
Item number: ATA-HPA023197.100
Protein function: Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797). Component of SWI/SNF chromatin remodeling...
| Keywords: | Anti-BRD9, Anti-Bromodomain-containing protein 9, Anti-Rhabdomyosarcoma antigen MU-RMS-40.8 |
| Application: | IHC, ChIP |
| Host: | Rabbit |
| Species reactivity: | human |
From 246.00€
*
PROTAC(R) Optimization Kit for BRD9-Cereblon Binding
Item number: BPS-78420
The PROTAC Optimization Kit for BRD9-Cereblon Binding is designed for the testing and profiling of PROTACs directed against BRD9 and Cereblon (CRBN). The BRD9 inhibitor BI-7273 is included as a control inhibitor of PROTAC binding to BRD9. With this kit, three simple steps are required for the measurement of PROTAC...
| Keywords: | BRD9, Bromodomain-containing protein 9, Rhabdomyosarcoma antigen MU-RMS-40.8, |
| Application: | BRD9 targeting PROTAC discovery/optimization, CRBN targeting molecule design, PROTAC act. comparison |
| Species reactivity: | human |
1,351.00€
*