29 products were found matching "K22184"!

Description: BI-9564, a specific cell-permeable BRD9 BD inhibitor. The Kd for BRD9 is 5.9 nM, and IC50 for BET family is > 100 µM. Target: Epigenetic Reader Domain. Smiles: COc1cc(c(OC)cc1CN(C)C)-c1cn(C)c(=O)c2cnccc12. References: Martin LJ, et al. J Med Chem. 2016, 59(10):4462-75.

Description: I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3. Target: Epigenetic Reader Domain. Smiles: CCn1cc(-c2cccc(c2)C(F)(F)F)c2sc(cc2c1=O)C(=N)NC1CCS(=O)(=O)CC1. References: Theodoulou NH, et al. J Med Chem. 2016, 59(4):1425-1439.

Protein function: May play a role in chromatin remodeling and regulation of transcription. [The UniProt Consortium]

Human Bromodomain containing 9, also known as BRD9, amino-acids 135-242 (GenBank Accession No. NM_023924) with N-terminal HIS tag, MW = 13.4 kDa, expressed in an E. coli expression system.

Human Bromodomain containing 9, also known as BRD9, amino-acids 135 ? 242 (GenBank Accession No. NM_023924) with N-terminal GST tag, MW = 39 kDa, expressed in an E. coli expression system.

The BRD9 TR-FRET Assay Kit is designed to measure the inhibition of BRD9 binding to its substrate in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward and...

May play a role in chromatin remodeling and regulation of transcription. Protein function: Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or...

May play a role in chromatin remodeling and regulation of transcription. Protein function: Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or...

Protein function: Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797). Component of SWI/SNF chromatin remodeling...

Protein function: Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797). Component of SWI/SNF chromatin remodeling...

The PROTAC Optimization Kit for BRD9-Cereblon Binding is designed for the testing and profiling of PROTACs directed against BRD9 and Cereblon (CRBN). The BRD9 inhibitor BI-7273 is included as a control inhibitor of PROTAC binding to BRD9. With this kit, three simple steps are required for the measurement of PROTAC...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Bromodomain-containing protein 9 is a protein that in humans is encoded by the BRD9 gene. Enables lysine-acetylated histone binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of SWI/SNF...