47 products were found matching "K19946"!

Description: Optineurin Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with C-9xHis tag. The predicted molecular weight is 68.0 kDa and the accession number is Q96CV9.

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis,...

Optineurin, originally named FIP-2, is a 74 kDa protein implicated in signal transduction of the tumor necrosis factor (TNF) pathway as well as membrane traffic regulation and cellular morphogenesis. Optineurin protein is also involved in apoptosis, although the exact role is currently unknown. Increased apoptosis...

Protein function: Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Negatively regulates the induction of IFNB in...

Protein function: Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Negatively regulates the induction of IFNB in...

Optineurin (originally named FIP-2) is a 74 kDa protein implicated in signal transduction of the tumor necrosis factor (TNF) pathway as well as membrane traffic regulation and cellular morphogenesis. Optineurin protein is also involved in apoptosis, although the exact role is currently unknown. Increased apoptosis...

Protein function: Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Negatively regulates the induction of IFNB in...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. OPTN is also known as NRP, FIP2 or HYPL. This gene encodes the coiled-coil containing protein Optineurin which may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may...

Optineurin (OPTN) is an adapter protein with roles in autophagy, vesicular trafficking, and inflammatory responses to viral and bacterial pathogens. OPTN binds to ubiquitinated cargo via its ubiquitin-binding domain and targets them for autophagic degradation by recruiting LC3-expressing phagophore membranes via its...

Protein function: Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8 (PubMed:27534431). Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation (PubMed:27534431). Plays a role in...

Protein function: Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8 (PubMed:27534431). Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation (PubMed:27534431). Plays a role in...

Protein function: Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8 (PubMed:27534431). Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation (PubMed:27534431). Plays a role in...