28 products were found matching "K16835"!

Anacetrapib is an inhibitor of cholesterol ester transfer protein (CETP) with IC50 values of 17 and 15 nM for CETP-dependent transfer of cholesterol esters and triglycerides, respectively. It decreases plasma levels of LDL and triglycerides, reduces atherosclerotic lesion sizes, and increases HDL levels in the...

Evacetrapib is a benzazepine inhibitor of cholesteryl ester transfer protein (CETP, IC50s = 5.5 and 26 nM for human recombinant and plasma-derived proteins, respectively). It is selective for CETP over a panel of cell surface and nuclear receptors with no significant inhibition at 1 µM. Evacetrapib (1-10 µM) reduces...

Torcetrapib is an inhibitor of cholesteryl ester transfer protein (CETP, IC50s = 47 and 51 nM for cholesteryl and triglyceride transfer, respectively). It is selective for CETP over phospholipid transfer protein (PLTP), lecithin:cholesterol acyltransferase (LCAT), and hepatic and lipoprotein lipases at 10 µM....

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 18-493aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal MBP-tagged and C-terminal 6xHis-tagged. Target Protein Sequence: CSKGTSHEAG IVCRITKPAL LVLNHETAKV IQTAFQRASY PDITGEKAMM LLGQVKYGLH NIQISHLSIA SSQVELVEAK SIDVSIQNVS...

Protein function: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride...

Cholesterol ester transfer protein inhibitor.

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cholesteryl Ester Transfer Protein Plasma, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. CETP is also known as lipid transfer protein I(Day et al., 1994). Sparkes et al.(1987) used a CETP...

Isolated from Chaetomium sp. Soluble in DMSO, methanol, chloroform or acetone. Azaphilone antibiotic. Antifungal compound (phytopathogenic fungi). Cholesteryl ester transfer protein (CETP) inhibitor. Improves blood lipid levels. Monoamine oxidase inhibitor.

Cholesteryl ester transfer protein (CETP) is an exchange protein which transfers cholesteryl esters from HDL to VLDL, IDL, and LDL in exchange for triglycerides. Dalcetrapib is an inhibitor of CETP that exhibits an IC50 value of 9 µM for plasma CETP in rabbits. Inhibition of CETP by dalcetrapib in rabbits given an...

ELISA Type: CLIA. Sensitivity: 37.5 pg/mL. Range: 62.5--4000 pg/mL. Protein function: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low...

ELISA Type: Sandwich. Sensitivity: 0.188ng/mL. Range: 0.313--20ng/mL. Protein function: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low...