8 products were found matching "K13998"!
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Pyrimethamine
Item number: Cay16472-10
Pyrimethamine is an antiprotozoal agent that is primarily active against P. falciparum, inhibiting the protozoal enzyme dihydrofolate reductase (DHFR). By blocking DHFR activity, pyrimethamine prevents the production of tetrahydrofolic acid, an essential coenzyme involved in DNA and RNA synthesis. In in vivo...
| Keywords: | Darapram, Daraprim(R), Khloridin, NSC 3061, 5,4-chlorophenyl-6-ethyl-2,4-pyrimidinediamine |
| Application: | Protozoal dihydrofolate reductase (DHFR) inhibitor |
| CAS | 58-14-0 |
| MW: | 248.7 D |
From 49.00€
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Diaveridine
Item number: Cay29427-500
Diaveridine is a dihydrofolate reductase (DHFR) inhibitor (Ki = 11.5 nM for the P. falciparum enzyme) with antimicrobial activity. It is active against P. vulgaris, S. aureus, and S. pyogenes in vitro (MICs = 4, 1, and 2 µg/ml, respectively). Diaveridine has anticoccidial activity when administered alone or in...
| Keywords: | NSC 408735, 5-[(3,4-dimethoxyphenyl)methyl]-2,4-pyrimidinediamine |
| Application: | Antiparasitic, dihydrofolate reductase inhibitor |
| CAS | 5355-16-8 |
| MW: | 260.3 D |
From 56.00€
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Proguanil
Item number: Cay30675-10
Proguanil is a prodrug form of the antimalarial agent cycloguanil (Cay-16861). Proguanil is metabolized by the cytochrome P450 (CYP) isoforms CYP2C19 and CYP3A to form cycloguanil in human liver microsomes. It is active against chloroquine- and quinine-resistant strains of P. falciparum alone or in combination with...
| Keywords: | Chlorguanide, Chloroguanide, N-(4-chlorophenyl)-N'-(1-methylethyl)-imidodicarbonimidic diamide |
| Application: | Cycloguanil prodrug |
| CAS | 500-92-5 |
| MW: | 253.7 D |
From 72.00€
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Proguanil hydrochloride
Item number: TGM-T4382-100mg
Description: Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguanil hydrochloride is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction. Cycloguanil...
| Keywords: | Paludrine hydrochloride, Chlorguanide hydrochloride, Chloroquanil |
| Application: | Targets dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45] (DHFR-TS) |
| CAS | 637-32-1 |
| MW: | 290.19 D |
From 32.00€
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Anti-THY-2
Item number: CSB-PA275245XA01DOA.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Keywords: | Anti-THY-2, Anti-DHFR-TS 2, Anti-T4L20.150, Anti-At4g34570, EC=1.5.1.3, EC=2.1.1.45, Anti-Thymidylate synthase,... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | Arabidopsis thaliana (Mouse-ear cress) |
1,529.00€
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Anti-THY-1
Item number: CSB-PA216163XA01DOA.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Keywords: | Anti-THY-1, Anti-F16F14.13, Anti-DHFR-TS 1, Anti-At2g16370, EC=1.5.1.3, EC=2.1.1.45, Anti-Thymidylate synthase,... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | Arabidopsis thaliana (Mouse-ear cress) |
From 1,529.00€
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Anti-DRTS
Item number: CSB-PA528064XA01ZAX.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Keywords: | Anti-DRTS, Anti-DHFR-TS, EC=1.5.1.3, EC=2.1.1.45, Anti-Thymidylate synthase, Anti-Dihydrofolate reductase,... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | Zea mays (Maize) |
From 1,529.00€
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Proguanil
Item number: TGM-T22409-5mg
Description: Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the dihydrofolate reductase (DHFR) enzyme of Plasmodium falciparum, preventing the synthesis of purines and pyrimidines and inhibiting the growth and reproduction...
| Keywords: | Chloroguanide , Chlorguanide |
| Application: | Targets dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45] (DHFR-TS) |
| CAS | 500-92-5 |
| MW: | 253.73 D |
From 34.00€
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