54 products were found matching "K12348"!
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SABRAC
Item number: TGM-T68441-10mg
Description: SABRAC inhibits acid ceramidase in PC3 MC metastatic prostate cancer cells (IC50 = <1 µM), as well as induces accumulation of ceramides in the same cells. Target: Others. Smiles: [C@H]([C@@H](CCCCCCCCCC CCCCC)O)(NC(CBr)=O)CO
| Application: | Acid ceramidase inhibitor |
| CAS | 886212-98-2 |
| MW: | 422.44 D |
From 158.00€
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SACLAC
Item number: TGM-T83653-100mg
Description: SACLAC is a cysteine asparaginase activation inhibitor with antitumor activity that decreases AML cell viability, inhibits AML cell proliferation, increases AML cell death, and induces apoptosis of AML cells, and is used in the study of acute myeloid leukemia and cancer. Target: Apoptosis, Caspase....
| Application: | Acid ceramidase inhibitor |
| CAS | 2248703-42-4 |
| MW: | 377.99 D |
From 194.00€
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SOCLAC
Item number: TGM-T84961-10mg
Description: SOCLAC, a derivative of the acid ceramidase inhibitor SABRAC, functions as an irreversible inhibitor of acid ceramidase with an inhibition constant (Ki) of 40.2 nM. Target: Others. Smiles: [C@H]([C@@H](/C=C/CCCCCCCCCC CCC)O)(NC(CCl)=O)CO
| Keywords: | N-chloroacetyl Sphingosine |
| Application: | Acid ceramidase inhibitor |
| CAS | 126586-82-1 |
| MW: | 376 D |
Please request pricing for this article.
SOBRAC
Item number: TGM-T84964-10mg
Description: SOBRAC, a derivative of the acid ceramidase inhibitor SABRAC, acts as an irreversible inhibitor of acid ceramidase (Ki= 29.7 nM). Target: Others. Smiles: [C@H]([C@@H](/C=C/CCCCCCCCCC CCC)O)(NC(CBr)=O)CO
| Application: | Acid ceramidase inhibitor |
| CAS | 362678-28-2 |
| MW: | 420.4 D |
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ASAH1 Protein, Human, Recombinant (His & SUMO)
Item number: TGM-TMPH-00880-100ug
Description: ASAH1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 58.7 kDa and the accession number is Q13510.
| Keywords: | N-acylsphingosine amidohydrolase, Acylsphingosine deacylase, Acid CDase, HSD33, AC, ASAH1, ACDase, HSD-33, ASAH, Acid... |
| MW: | 58.7 kD |
From 198.00€
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ASAH1 Protein, Mouse, Recombinant (GST & His & Myc)
Item number: TGM-TMPH-02490-100ug
Description: ASAH1 Protein, Mouse, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10XHis-GST and C-Myc tag. The predicted molecular weight is 43.8 kDa and the accession number is Q9WV54.
| Keywords: | ASAH, Acid CDase, ASAH1, HSD-33, Acid ceramidase, N-acylsphingosine amidohydrolase, AC, PHP32, HSD33, ACDase,... |
| MW: | 43.8 kD |
From 281.00€
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LCL521
Item number: TGM-T11835-100mg
Description: LCL521 inhibits lysosomal acid sphingomyelinase (ASMase).LCL521 is an acid ceramidase (ACDase) inhibitor. Target: Others, Phospholipase. Smiles: [C@@H]([C@H](NC(CCCCCCCCCC CCC)=O)COC(CN(C)C)=O)(OC(CN(C)C)=O)C1=CC=C(N(=O)=O)C=C1. References: Bai A, et al. Targeting (cellular) lysosomal acid ceramidase...
| Application: | Acid ceramidase inhibitor |
| CAS | 1226851-11-1 |
| MW: | 592.77 D |
From 986.00€
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ARN14974
Item number: TGM-T21658-1mg
Description: ARN14974 is a benzoxazolone carboxamide. ARN14974 is a potent inhibitor of acid ceramidase with IC50 of 79 nM[1]. Target: Others. Smiles: Fc1ccc(cc1)-c1ccc2n(C(=O)NCCCCc3ccccc3)c(=O)oc2c1. References: Bach A, Pizzirani D, Realini N, Vozella V, Russo D, Penna I, Melzig L, Scarpelli R, Piomelli D....
| Application: | Acid ceramidase inhibitor |
| CAS | 1644158-57-5 |
| MW: | 404.43 D |
From 40.00€
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ARN14988
Item number: TGM-T36468-10mg
Description: ARN14988 is a potent inhibitor of acid ceramidase (IC50 = 12.8 nM for the human enzyme). It inhibits acid ceramidase activity and increases levels of C16 dihydro ceramide and C16 ceramide in A375, G361, M14, MeWo, MNT-1, and SK-MEL-28 melanoma cells. ARN14988 also reduces growth of A375 and G361...
| Application: | Acid ceramidase inhibitor |
| CAS | 1502027-70-4 |
| MW: | 373.83 D |
From 108.00€
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C12-Ceramide
Item number: TGM-T37436-10mg
Description: C12-Ceramide (C12 Ceramide (d18:1/12:0)), a ceramide present in the protective membranes surrounding umbilical cord blood vessels in infants born to women with pre-eclampsia, can be used to assess the level of ASM activity in the plasma of patients with Niemann-Pick disease. Smiles: CCCCCCCCCC...
| Keywords: | N-Laurylsphingosine, C12 Ceramide (d18:1/12:0), N-Lauroyl-D-erythro-sphingosine |
| Application: | Acid ceramidase substrate |
| CAS | 74713-60-3 |
| MW: | 481.79 D |
From 145.00€
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Anti-ASAH1
Item number: CSB-PA208943.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ASAH1. Antigen Species: Human
| Keywords: | Anti-ASAH, Anti-HSD-33, AC antibody, ACDase antibody, Acid CDase antibody, Acid ceramidase antibody, Acid ceramidase... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Anti-ASAH1
Item number: CSB-PA578122.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ASAH1. Antigen Species: Human
| Keywords: | Anti-ASAH, Anti-HSD-33, AC antibody, ACDase antibody, Acid CDase antibody, Acid ceramidase antibody, Acid ceramidase... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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