150 products were found matching "K11793"!
No results were found for the filter!
NEW
Recombinant Human Cereblon
Item number: SCC-MB7708
Human Cereblon (CRBN) serves as the substrate receptor of the DDB1-CUL4-RBX1 (CRL4CRBN) E3 ubiquitin ligase complex, where it mediates the recognition and ubiquitination of numerous target proteins, including ILF2 and MEIS2. Upon substrate binding, CRBN recruits target proteins to the E3 ligase complex, promoting...
| Keywords: | 6xHis-CRBN, Protein cereblon, AD-006, CRBN, CRBN, Protein cereblon |
| Origin: | human |
From 182.00€
*
Anti-CRBN
Item number: ABS-KC-51165.100
Formulation: Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide. Identity-Mouse (%): . Homologies: . IHC Verification: -. WB Verification: -. IP Verification: -. IF Verification: -. FC Verification: -. IP-MS Verification: succeed. Cross reactivity: Not tested. Sandwich ELISA...
| Keywords: | Anti-CRBN, Anti-Protein cereblon, CRBN Antibody |
| Application: | IP-MS |
| Host: | Rabbit |
| Species reactivity: | human |
From 232.00€
*
CRBN-6-5-5-VHL
Item number: Cay45748-1
CRBN-6-5-5-VHL is a proteolysis-targeting chimera (PROTAC) containing the cereblon (CRBN) inhibitor pomalidomide (Cay-19877) and the von Hippel-Lindau (VHL) E3 ligase ligand VH 032 (Cay-39982). It selectively induces the degradation of CRBN over Ikaros family zinc finger protein 1 (IKZF1) in MM.1S cells at 10-500...
| Keywords: | Cereblon-6-5-5-VHL, Cereblon-6-5-5-von, CRBN-6-5-5-von, Hippel-Lindau,... |
| Application: | Cereblon (CRBN) degradation driving PROTAC |
| CAS | 2362575-45-7 |
| MW: | 972.21 D |
From 174.00€
*
CRBN/DDB1 Complex (human, recombinant)
Item number: Cay45180-100
Source: Active recombinant human N-terminal His-AVI-tagged CRBN and DDB1 expressed in insect cells . Amino acids: 1-442 (CRBN) (full length), 1-1,140 (DDB1) (full length) . MW: 55.3 (CRBN) and 126.9 (DDB1) kDa. Protein Function: Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex...
| Keywords: | CRBN, Protein cereblon |
From 1,294.00€
*
CRBN/DDB1/Cullin 4A/RBX1 Complex (human, recombinant)
Item number: Cay45181-50
Source: Active recombinant human N-terminal His-AVI-tagged CRBN, DDB1, cullin 4A, and RBX1 expressed in insect cells . Amino acids: 1-442 (CRBN) (full length), 1-1,140 (DDB1) (full length), 2-759 (cullin 4A) (full length), 1-108 (RBX1) (full length) . MW: 55.3 (CRBN), 126.9 (DDB1), 87.6 (cullin 4A), and 12.2 (RBX1)...
| Keywords: | CRBN, Protein cereblon |
1,354.00€
*
Cereblon/CRBN Protein, Human, Recombinant (Cell-Free, His)
Item number: TGM-TMPH-01931-10ug
Description: Cereblon/CRBN Protein, Human, Recombinant (Cell-Free, His) is expressed in in vitro E. coli expression system.
| Keywords: | CRBN , Protein cereblon |
| MW: | 51.2 kD |
From 260.00€
*
Cereblon/CRBN Protein, Human, Recombinant (His)
Item number: TGM-TMPH-01932-10ug
Description: Cereblon/CRBN Protein, Human, Recombinant (His) is expressed in Baculovirus.
| Keywords: | CRBN , Protein cereblon |
| MW: | 53.4 kD |
From 149.00€
*
Cereblon/CRBN Protein, Rat, Recombinant (His)
Item number: TGM-TMPH-03356-10ug
Description: Cereblon/CRBN Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 52.4 kDa and the accession number is Q56AP7.
| Keywords: | Protein cereblon , Crbn |
| MW: | 52.4 kD |
From 273.00€
*
TD-106
Item number: Cay44836-10
TD-106 is a modulator of cereblon. It binds to cereblon in a cellular thermal shift assay (CETSA) using HEK293 cells. TD-106 (1-1,000 nM) induces degradation of the cereblon targets Ikaros family zinc finger protein 1 (IKZF1) and IKZF3 in NCI H929 multiple myeloma cells and is cytotoxic to NCI H929 cells (CC50 = 0....
| Keywords: | 3-(5-amino-4-oxo-1,2,3-benzotriazin-3(4H)-yl)-2,6-piperidinedione |
| Application: | Cereblon modulator |
| CAS | 2250288-69-6 |
| MW: | 273.25 D |
From 244.00€
*
TD-165
Item number: Cay44837-1
TD-165 is a proteolysis-targeting chimera (PROTAC) that contains VH 032 (Cay-39982) conjugated to the cereblon (CRBN) inhibitor pomalidomide (Cay-19877). It induces degradation of CRBN in HEK293T cells with a half-maximal degradation concentration (DC50) value of 20. nM. TD-165 (0. µM) increases L-type voltage-gated...
| Keywords: | (2S,4R)-1-((2S)-2-(11-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)undecanamido)-3,3-dimethyl-butanoyl)-4-... |
| Application: | CRBN degradation driving PROTAC |
| CAS | 2305936-56-3 |
| MW: | 870.08 D |
From 79.00€
*
CRBNmidi (human, recombinant)
Item number: Cay45179-10
Source: Recombinant human N-terminal His-tagged CRBNmidi expressed in E. coli Amino acids: 41-187-GSG-249-426 MW: 39.8 kDa. SMILES: . InChi Code: . InChi Key:
| Keywords: | Cereblonmidi |
| Expressed in: | E. coli |
From 356.00€
*
Anti-CRBN / Cereblon
Item number: NSJ-FY12446
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. CRBN antibody recognizes Cereblon, a substrate receptor component of the CRL4 E3 ubiquitin ligase complex that plays a central role in targeted protein degradation. Cereblon binds to the DDB1-CUL4-ROC1 complex, recruiting specific substrates...
| Keywords: | Anti-CRBN, Anti-Protein cereblon, CRBN Antibody / Cereblon |
| Application: | WB, ICC/IF, FC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
790.00€
*