36 products were found matching "K11436"!

Active human PRMT3, GenBank Accession No. NM_005788, amino-acids 2-end, with N-terminal GST tag, MW=86 kDa, expressed in an E. coli expression system.

Protein function: Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins. [The UniProt Consortium]

Protein function: Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins. [The UniProt Consortium]

Protein arginine N-methyltransferase 3 (PRMT3, Cay-11642) is a predominantly cytoplasmic enzyme that is constitutively expressed. SGC707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets. Developed by the Structural...

Protein arginine N-methyltransferase 3 (PRMT3, Cay-11642) is a predominantly cytoplasmic enzyme that is constitutively expressed. SGC707 (Cay-17017) is a potent, selective allosteric inhibitor of PRMT3 (IC50 = 50 nM). It inhibits the methylation of histones in cells with an IC50 value below 1 µM. XY1 is a close...

UNC2327 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3, IC50 = 230 nM).Formal Name: N-1,2,3-benzothiadiazol-6-yl-N'-[2-oxo-2-(1-piperidinyl)ethyl]-urea. CAS Number: 1426152-53-5. Molecular Formula: C14H17N5O2S. Formula Weight: 319.4. Purity: >98%. Formulation: (Request formulation change),...

The PRMT3 Homogenous Assay Kit is designed to measure activity of the PRMT3 using purified enzyme complex or cell extracts containing PRMT3. PRMT3 is a histone methyltransferase that exhibits methylation activity toward H4-R3. The PRMT3 Homogenous Assay Kit comes in a convenient AlphaScreen or AlphaLISA format, with...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Protein arginine methyltransferase 3 Protein function: Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins. [The UniProt Consortium]

In 1X PBS, pH 7.4, with 0.09% sodium azide. Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory...

Type I protein arginine N-methyltransferases (PRMTs), such as PRMT3, catalyze the formation of asymmetric N(G),N(G)-dimethylarginine (ADMA) residues in proteins (Tang et al., 1998 [PubMed 9642256]). Protein function: Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some...

Protein function: Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 92%