148 products were found matching "K11411"!
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Anti-phospho-SIRT1 (Ser47)
Item number: CSB-PA857953.100
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy (PubMed:11672523,...
| Keywords: | Anti-phospho-SIR2L1, Phospho-SIRT1 (Ser47) Antibody |
| Application: | ELISA, WB |
| Species reactivity: | human |
320.00€
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NAD-dependent protein deacetylase sirtuin-1 (SIRT1),...
Item number: CSB-MP822202HU.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 2-747aa. Protein Length: Full Length of Mature Protein. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: ADEAALALQP GGSPSAAGAD REAASSPAGE PLRKRPRRDG PGLERSPGEP GGAAPEREVP AAARGCPGAA AAALWREAEA EAAAAGGEQE AQATAAAGEG DNGPGLQGPS...
| Keywords: | SIR2L1 |
| Application: | Activity not tested |
| Expressed in: | Mammalian cells |
| Origin: | human |
| MW: | 83.3 kD |
From 371.00€
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Anti-SIRT1
Item number: ABS-KC-924.100
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy (PubMed:11672523,...
| Keywords: | Anti-NAD-dependent protein deacetylase sirtuin-1, Anti-hSIRT1, Anti-NAD-dependent protein deacylase sirtuin-1,... |
| Host: | Mouse |
| Species reactivity: | human |
From 232.00€
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Anti-SIRT1
Item number: ABS-KC-974.100
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy (PubMed:11672523,...
| Keywords: | Anti-NAD-dependent protein deacetylase sirtuin-1, Anti-hSIRT1, Anti-NAD-dependent protein deacylase sirtuin-1,... |
| Host: | Mouse |
| Species reactivity: | human, mouse |
From 232.00€
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Anti-SIRT1
Item number: ABS-KC-6173.100
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy (PubMed:11672523,...
| Keywords: | Anti-NAD-dependent protein deacetylase sirtuin-1, Anti-hSIRT1, Anti-NAD-dependent protein deacylase sirtuin-1,... |
| Host: | Mouse |
| Species reactivity: | human |
From 232.00€
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SIRT1 Direct Fluorescent Screening Assay Kit
Item number: Cay10010401-96
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
| Keywords: | SIRT1, hSIR2, hSIRT1, SIR2L1, EC=3.5.1.-, SIR2-like protein 1, NAD-dependent deacetylase sirtuin-1 |
| Application: | SIRT1 inhibitor/activator screening |
| Species reactivity: | human |
476.00€
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BML-278
Item number: TGM-T77697-100mg
Description: BML-278 is a SIRT1 activator with an EC150 of 1 µM. It increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, improving early embryonic development. BML-278 induces cell cycle arrest at the G1/S phase in primary human mesenchymal stromal cells, delaying...
| Keywords: | BML278, BML 278 |
| Application: | SIRT1 activator |
| CAS | 120533-76-8 |
| MW: | 391.46 D |
From 58.00€
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Sirtuin-1 inhibitor 1
Item number: TGM-T79903-1mg
Description: Sirtuin-1 inhibitor 1 is an inhibitor against deacetylase-1 (Sirtuin-1) and can be used to study senescence and cell death in the organism. Target: Sirtuin. Smiles: O=C(NC=1C=CC=CC1)NC2=CC=C(C=C2)NC(=O)C=3C=CC=CC3. References: Anastasiia Gryniukova, et al. AI-Powered Virtual Screening of Large Compound...
| Application: | Sirtuin-1 inhibitor |
| CAS | 945114-10-3 |
| MW: | 331.37 D |
98.00€
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YK-3-237
Item number: TGM-T9320-100mg
Description: YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferative effects toward triple-negative breast cancer (TNBC) cells carrying mtp53. Target: Sirtuin. Smiles: COc1ccc(\C=C\C(=O)c2cc(OC)c(OC)c(OC)c2)cc1B(O)O
| Keywords: | B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid |
| Application: | SIRT1 activator |
| CAS | 1215281-19-8 |
| MW: | 372.18 D |
From 34.00€
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3,4',5-Trismethoxybenzophenone
Item number: TGM-T84553-10mg
Description: 3,4',5-Trismethoxybenzophenone (compound 16a) is an effective inhibitor of tubulin assembly, demonstrating a half-maximal inhibitory concentration (IC 50) of 2.6 µM [1]. Target: Others. Smiles: C(=O)(C1=CC(OC)=CC(OC)=C1)C2=CC=C(OC)C=C2
| Application: | Antioxidant, antiproliferative agent |
| CAS | 94709-12-3 |
| MW: | 272.3 D |
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Inauhzin
Item number: TGM-T1887-100mg
Description: Inauhzin (INZ)(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human Y cells without causing apparently genotoxic stress(IC50=3 uM, in A549 cell). Target: Sirtuin. Smiles:...
| Keywords: | INZ |
| Application: | Cell-permeable SIRT1 inhibitor |
| CAS | 309271-94-1 |
| MW: | 469.58 D |
From 37.00€
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Sirtinol
Item number: TGM-T6671-100mg
Description: Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 µM). Target: Apoptosis, Sirtuin, Autophagy. Smiles: CC(NC(=O)C1=C(C=CC=C1)\N=C\C1=C(O)C=CC2=CC=CC=C12)C1=CC=CC=C1. References: Grozinger CM, et al. J Biol Chem, 2001, 276(42), 38837-38843.
| Application: | Sirtuin-1 inhibitor |
| CAS | 410536-97-9 |
| MW: | 394.47 D |
From 37.00€
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