40 products were found matching "K10579"!
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WS-383
Item number: Cay45391-10
An inhibitor of the protein-protein interaction between DCNL1-UBC12 (IC50 = 11 nM in a cell-free assay), selectively inhibits neddylation of cullin-3 and -1 over other cullin proteins and increases levels of p21, p27, and Nrf2 in MGC803 cells at 10 µM, inhibits LSD1 activity in a cell-free assay (IC50 = 288 nM),...
| Keywords: | 5-[[2-[[(4-chlorophenyl)methyl]thio]-5-... |
| Application: | DCNL1-UBC12 protein-protein interaction inhibitor |
| CAS | 2247544-02-9 |
| MW: | 498.5 D |
From 147.00€
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Anti-UBC12 (Ubiquitin-conjugating enzyme E2M)
Item number: 600-401-865
Protein function: Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2,...
| Keywords: | Anti-UBE2M, Anti-UBC12, EC=6.3.2.-, Anti-NEDD8 protein ligase, Anti-NEDD8 carrier protein, Anti-NEDD8-conjugating enzyme... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human |
733.00€
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Anti-UBE2M
Item number: ATA-HPA054551.100
Protein function: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2,...
| Keywords: | Anti-UBC12, Anti-UBE2M, Anti-NEDD8 carrier protein, Anti-NEDD8-conjugating enzyme Ubc12, Anti-Ubiquitin-conjugating enzyme... |
| Application: | ICC, IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
491.00€
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Anti-UBE2M
Item number: ATA-HPA057800.100
Protein function: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2,...
| Keywords: | Anti-UBC12, Anti-UBE2M, Anti-NEDD8 carrier protein, Anti-NEDD8-conjugating enzyme Ubc12, Anti-Ubiquitin-conjugating enzyme... |
| Application: | ICC, IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
491.00€
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Anti-UBE2M / UBC12
Item number: NSJ-RQ7468
0.5mg/ml if reconstituted with 0.2ml sterile DI water. NEDD8-conjugating enzyme Ubc12 is a protein that in humans is encoded by the UBE2M gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at...
| Keywords: | Anti-UBC12, Anti-UBE2M, Anti-NEDD8 carrier protein, Anti-NEDD8-conjugating enzyme Ubc12, Anti-Ubiquitin-conjugating enzyme... |
| Application: | WB, IHC (paraffin), IF, FC, Direct ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
790.00€
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UBE2M Protein, Human, Recombinant
Item number: TGM-TMPY-02609-100ug
Description: UBE2M is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation, ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the...
| Keywords: | ubiquitin-conjugating enzyme E2M, UBC-RS2, UBC12, hUbc12 |
| MW: | 21 kD |
545.00€
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Anti-UBE2M
Item number: ABS-KC-3445.100
Protein function: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2,...
| Keywords: | Anti-NEDD8-conjugating enzyme Ubc12, Anti-NEDD8 carrier protein, Anti-Ubiquitin-conjugating enzyme E2 M, UBE2M Antibody |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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Anti-UBE2M
Item number: ABS-KC-3460.100
Protein function: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2,...
| Keywords: | Anti-NEDD8-conjugating enzyme Ubc12, Anti-NEDD8 carrier protein, Anti-Ubiquitin-conjugating enzyme E2 M, UBE2M Antibody |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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Anti-Human UBE2M Antibody Pair
Item number: ABS-ES-2164.1
Product Description: Ubiquitin conjugating enzyme E2 M (UBE2M), also known as Ubc12, is a crucial mediator in the NEDD8 conjugation pathway. It accepts NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins, particularly cullins. UBE2M is highly conserved across species and plays...
| Keywords: | Anti-UBE2M, Anti-NEDD8 carrier protein, Anti-NEDD8-conjugating enzyme Ubc12, Anti-Ubiquitin-conjugating enzyme E2 M, Human... |
| Application: | ELISA |
| Host: | Mouse/Mouse |
| Species reactivity: | human |
1,080.00€
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Anti-Human UBE2M Antibody Pair
Item number: ABS-ES-2165.1
Product Description: Ubiquitin conjugating enzyme E2 M (UBE2M), also known as Ubc12, is a crucial mediator in the NEDD8 conjugation pathway. It accepts NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins, particularly cullins. UBE2M is highly conserved across species and plays...
| Keywords: | Anti-UBE2M, Anti-NEDD8 carrier protein, Anti-NEDD8-conjugating enzyme Ubc12, Anti-Ubiquitin-conjugating enzyme E2 M, Human... |
| Application: | ELISA |
| Host: | Mouse/Mouse |
| Species reactivity: | human |
1,080.00€
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Anti-Human UBE2M Antibody Pair
Item number: ABS-ES-2163.1
Product Description: Ubiquitin conjugating enzyme E2 M (UBE2M), also known as Ubc12, is a crucial mediator in the NEDD8 conjugation pathway. It accepts NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins, particularly cullins. UBE2M is highly conserved across species and plays...
| Keywords: | Anti-UBE2M, Anti-NEDD8 carrier protein, Anti-NEDD8-conjugating enzyme Ubc12, Anti-Ubiquitin-conjugating enzyme E2 M, Human... |
| Application: | ELISA |
| Host: | Mouse/Mouse |
| Species reactivity: | human |
1,080.00€
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NEW
Recombinant Human UBE2M/UBC12 Protein (RPES4420)
Item number: G-RPES4420.100
Protein function: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2,...
| Keywords: | UBE2M, UBC12, NEDD8 carrier protein, NEDD8-conjugating enzyme Ubc12, Ubiquitin-conjugating enzyme E2 M |
| Expressed in: | E.coli |
| Origin: | human |
1,122.00€
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