46 products were found matching "K08552"!

SLU-PP-332 is an agonist of estrogen-related receptor alpha (ERRalpha), ERRbeta, and ERRgamma. It induces reporter gene expression in HEK293 cells expressing ERRalpha, ERRbeta, or ERRgamma (EC50s = 98, 230, and 430 nM, respectively). SLU-PP-332 (10 µM) increases mitochondrial respiration in C2C12 skeletal myoblasts....

The estrogen-related receptors (ERRs) are orphan nuclear receptors with homology to the estrogen receptor family and are expressed in tissues with high metabolic demand. Binding of peroxisome proliferator-activated receptor gamma-coactivator 1alpha (PGC-1alpha) to this class of receptors is known to potentiate ERR...

Protein function: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene...

This nuclear receptor assay system utilizes proprietary human mammalian cells engineered to provide high-level expression of a hybrid form of the human estrogen-related receptor alpha (NR3B1). The N-terminal DNA binding domains (DBD) of the native ERRalpha has been substituted with that of the yeast GAL4-DBD. The...

This nuclear receptor assay system utilizes proprietary human mammalian cells engineered to provide high-level expression of a hybrid form of the human estrogen-related receptor alpha (NR3B1). The N-terminal DNA binding domains (DBD) of the native ERRalpha has been substituted with that of the yeast GAL4-DBD. The...

XCT790 is an inverse agonist of estrogen-related receptor alpha (ERRalpha, IC50 = ~300-500 nM). It demonstrates 90-100% inhibition of ERRalpha constitutive activity and has no significant activity at related nuclear receptors at 10 µM. XCT790 associates with the ligand-binding domain of ERRalpha and blocks...

Protein function: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium- chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ERa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ERa. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ERRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ERRa. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ERa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ERa. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ERRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ERRa. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ERa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ERa. Next, Avidin...