12 products were found matching "K08428"!

TC-O 9311 is an agonist of the orphan G protein-coupled receptor GPR139 (EC50 = 39 nM in a calcium mobilization assay). It is selective for GPR139 over a panel of 90 additional targets. TC-O 9311 (1 µM) inhibits cell death induced by 1-methyl-4-phenylpyridinium (MPP+), but not 6-hydroxydopamine (6-OHDA, Cay-25330),...

JNJ-63533054 is a potent agonist of the orphan G protein-coupled receptor GPR139 (EC50 = 16 nM in HEK293 cells expressing human GPR139). It is selective for GPR139 over 50 known G protein-coupled receptors, ion channels, and transporters as determined by an external selectivity panel. Tritium-labeled JNJ-63533054...

This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript...

WB 1:500 - 1:2000. Protein function: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. [The UniProt Consortium]

Protein function: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%

TAK-041 is an agonist of G protein-coupled receptor 139 (GPR139). It induces calcium mobilization in cells expressing human GPR139 (EC50 = 22 nM). In vivo, TAK-041 (0.3 and 3 mg/kg) increases social interaction in mice.Formal Name:...

This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript...

This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript...

Orphan receptor. Seems to act through a G(q/11)-mediated pathway. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:4000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid...

Protein function: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.

Protein function: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. [The UniProt Consortium]

Custom conjugation services for this antibody as available (eg. labeling of Anti-GPR139 with HRP. Available labels are AF: AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750. Proteins: HRP, Alkaline Phosphatase, Streptavidin. Tandems: APC, APC/Cy7, APC/AF750, APC/iFluor(TM) 700, APC/iFluor(TM) 750, PE, PE/Cy5,...