64 products were found matching "K08155"!

Reserpine is an alkaloid isolated from dried roots of R. serpentine, which is used in traditional Indian medicine. Reserpine irreversibly inhibits both human isoforms of vesicular monoamine transporter, VMAT1 and VMAT2 (Kis = 34 and 12 nM, respectively). As this leads to metabolism of monoamines, reserpine is used...

Solulibility: DMSO: Sparingly Soluble: 1-10 mg/ml: Ethanol: Sparingly Soluble: 1-10 mg/ml.

Decynium-22 is an inhibitor of monoamine transporters and organic cation transporters (OCTs). It inhibits the plasma membrane monoamine, serotonin (5-HT), norepinephrine, and dopamine monoamine transporters (IC50s = 1.1, 7.9, 30, and 12.9 µM, respectively), and OCT2 and OCT3 (IC50s = 10 and 0.2 µM, respectively) in...

Tetrabenazine is an inhibitor of vesicular monoamine transporter 2 (VMAT2) that is selective over VMAT1 (Kis = 97 and >20,000 nM, respectively, in a serotonin uptake assay). It dose-dependently reduces levels of the monoamines norepinephrine (Cay-16673), dopamine (Cay-21992), and serotonin (5-HT, Cay-14332) in rat...

FFN-102 is a fluorescent false neurotransmitter (FFN) that is a substrate for the dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2). It is a pH-dependent fluorescent probe that labels dopamine cell bodies, axons, and presynaptic terminals. It can also be used to monitor dopamine exocytosis. It...

Protein function: Involved in the transport of biogenic monoamines, such as serotonin, from the cytoplasm into the secretory vesicles of neuroendocrine and endocrine cells. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity...

Protein function: Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis. [The UniProt Consortium]

Anti-Vesicular Monoamine Transporter 2 antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Anti-Vesicular Monoamine Transporter 2 Antibody is directed against rat Vesicular Monoamine Transporter 2. Cross reactivity with Vesicular Monoamine Transporter 2 from other species has...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Vesicular monoamine transporter 2, solute carrier family 18 (vesicular monoamine) member 2 (SLC18A2) Protein function: Involved in the ATP-dependent vesicular transport of biogenic amine...

Tetrabenazine-d7 is intended for use as an internal standard for the quantification of tetrabenazine (Cay-20380) by GC- or LC-MS. Tetrabenazine is an inhibitor of vesicular monoamine transporter 2 (VMAT2) that is selective over VMAT1 (Kis = 97 and >20,000 nM, respectively, in a serotonin uptake assay). It...