- Search results for K06711
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14 products were found matching "K06711"!
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Item number: Cay71210-100
The pro-angiogenic factor HIF-1alpha is targeted for destruction in normoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-1alpha prolyl hydroxylase (HIF-PH). DMOG is a cell permeable, competitive inhibitor of HIF-PH. It acts to stabilize HIF-1alpha...
Keywords: | Dimethyloxallyl Glycine, N-(methoxyoxoacetyl)-glycine, methyl ester |
Application: | HIF-PH inhibitor |
CAS | 89464-63-1 |
MW: | 175.1 D |
From 26.00€
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Item number: Cay71200-10
The pro-angiogenic factor HIF-1alpha is targeted for destruction in normoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-alpha prolyl hydroxylase (HIF-PH). 2,4-DPD is a cell permeable, competitive inhibitor of HIF-PH. 2,4-DPD inhibits the hydroxylation of...
Keywords: | 2,4-Diethylpyridine dicarboxylate, 2,4-pyridinedicarboxylic acid, diethyl ester |
Application: | HIF-PH inhibitor |
CAS | 41438-38-4 |
MW: | 223.2 D |
From 26.00€
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Item number: Cay14316-5
JNJ-42041935 is a selective, 2-OG competitive, and reversible inhibitor of HIF-PH enzymes (pKis = 12.3, 51.3, and 22.4 nM for HIF-PH1, HIF-PH2, and HIF-PH3, respectively). It is >100-fold selective for HIF-PH compared to the related FIH (factor-inhibiting HIF) and a panel of various other enzymes. In an...
Keywords: | HIF-PHD Inhibitor II, 1-[6-chloro-5-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1H-pyrazole-4-carboxylic acid |
Application: | HIF-PH4 inhibitor |
CAS | 1193383-09-3 |
MW: | 346.7 D |
From 84.00€
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Item number: Cay71220-10
The pro-angiogenic factor HIF-1alpha is targeted for destruction in non-hypoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-alpha prolyl hydroxylase (HIF-PH). Inhibitors of prolyl 4-hydroxylase are potentially useful in controlling excess collagen...
Keywords: | 1,4-dihydrophenonthrolin-4-one-3-Carboxylic acid, 4,4alpha-dihydro-4-oxo-1,10-phenanthroline-3-carboxylic acid |
Application: | Prolyl 4-hydroxylase inhibitor |
CAS | 331830-20-7 |
MW: | 240.2 D |
From 66.00€
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Item number: A300-330A
Protein function: Catalyzes the post-translational formation of 4- hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal...
Keywords: | Anti-PH4, Anti-P4HTM, Anti-HPH-4, Anti-P4H-TM, Anti-HIF-PH4, EC=1.14.11.-, Anti-HIF-prolyl hydroxylase 4,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: G-CAB13593.100
IF 1:50 - 1:200. Protein function: Catalyzes the post-translational formation of 4- hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for...
Keywords: | Anti-PH4, Anti-HPH-4, Anti-P4HTM, Anti-P4H-TM, Anti-HIF-PH4, Anti-HIF-prolyl hydroxylase 4, Anti-Transmembrane prolyl... |
Application: | IF |
Host: | Rabbit |
Species reactivity: | human |
From 352.00€
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Item number: G-CAB6143.100
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 352.00€
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Item number: ATA-HPA007199.100
Protein function: Catalyzes the post-translational formation of 4- hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal...
Keywords: | Anti-PH4, Anti-HPH-4, Anti-P4HTM, Anti-P4H-TM, Anti-HIF-PH4, Anti-HIF-prolyl hydroxylase 4, Anti-Transmembrane prolyl... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
446.00€
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Item number: ELK-ELK9846.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human P4HTM. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human P4HTM. Next,...
Keywords: | PH4, P4HTM, HPH-4, P4H-TM, HIF-PH4, HIF-prolyl hydroxylase 4, Transmembrane prolyl 4-hydroxylase, Hypoxia-inducible factor... |
Application: | ELISA |
Species reactivity: | human |
470.00€
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From 423.00€
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Item number: LKT-D6108.25
Prolyl hydroxylase inhibitor.
Keywords: | 1,4-Dihydrophenonthrolin-4-one-3-carboxylic acid, 3-Acetyl-1H-[1,10]phenanthrolin-4-one,... |
Application: | Prolyl hydroxylase inhibitor |
CAS | 331830-20-7 |
MW: | 240.22 D |
From 72.00€
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Item number: 374590.100
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von...
Keywords: | PH4, HPH-4, P4HTM, P4H-TM, HIF-PH4, HIF-prolyl hydroxylase 4, Transmembrane prolyl 4-hydroxylase, Hypoxia-inducible factor... |
MW: | 70,5 |
From 511.00€
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Item number: ATA-APrEST71314.100
Protein function: Catalyzes the post-translational formation of 4- hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal...
Keywords: | PH4, HPH-4, P4HTM, P4H-TM, HIF-PH4, HIF-prolyl hydroxylase 4, Transmembrane prolyl 4-hydroxylase, Hypoxia-inducible factor... |
Application: | Control antigen |
Expressed in: | E.coli |
Origin: | human |
247.00€
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