14 products were found matching "K06711"!

1 from 2 pages
No results were found for the filter!
DMOG
DMOG

Item number: Cay71210-100

The pro-angiogenic factor HIF-1alpha is targeted for destruction in normoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-1alpha prolyl hydroxylase (HIF-PH). DMOG is a cell permeable, competitive inhibitor of HIF-PH. It acts to stabilize HIF-1alpha...
Keywords: Dimethyloxallyl Glycine, N-(methoxyoxoacetyl)-glycine, methyl ester
Application: HIF-PH inhibitor
CAS 89464-63-1
MW: 175.1 D
From 26.00€ *
Review
2,4-DPD
2,4-DPD

Item number: Cay71200-10

The pro-angiogenic factor HIF-1alpha is targeted for destruction in normoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-alpha prolyl hydroxylase (HIF-PH). 2,4-DPD is a cell permeable, competitive inhibitor of HIF-PH. 2,4-DPD inhibits the hydroxylation of...
Keywords: 2,4-Diethylpyridine dicarboxylate, 2,4-pyridinedicarboxylic acid, diethyl ester
Application: HIF-PH inhibitor
CAS 41438-38-4
MW: 223.2 D
From 26.00€ *
Review
JNJ-42041935
JNJ-42041935

Item number: Cay14316-5

JNJ-42041935 is a selective, 2-OG competitive, and reversible inhibitor of HIF-PH enzymes (pKis = 12.3, 51.3, and 22.4 nM for HIF-PH1, HIF-PH2, and HIF-PH3, respectively). It is >100-fold selective for HIF-PH compared to the related FIH (factor-inhibiting HIF) and a panel of various other enzymes. In an...
Keywords: HIF-PHD Inhibitor II, 1-[6-chloro-5-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1H-pyrazole-4-carboxylic acid
Application: HIF-PH4 inhibitor
CAS 1193383-09-3
MW: 346.7 D
From 84.00€ *
Review
1,4-DPCA
1,4-DPCA

Item number: Cay71220-10

The pro-angiogenic factor HIF-1alpha is targeted for destruction in non-hypoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-alpha prolyl hydroxylase (HIF-PH). Inhibitors of prolyl 4-hydroxylase are potentially useful in controlling excess collagen...
Keywords: 1,4-dihydrophenonthrolin-4-one-3-Carboxylic acid, 4,4alpha-dihydro-4-oxo-1,10-phenanthroline-3-carboxylic acid
Application: Prolyl 4-hydroxylase inhibitor
CAS 331830-20-7
MW: 240.2 D
From 66.00€ *
Review
Anti-PHD4
Anti-PHD4

Item number: A300-330A

Protein function: Catalyzes the post-translational formation of 4- hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal...
Keywords: Anti-PH4, Anti-P4HTM, Anti-HPH-4, Anti-P4H-TM, Anti-HIF-PH4, EC=1.14.11.-, Anti-HIF-prolyl hydroxylase 4,...
Application: WB
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
Anti-P4HTM
Anti-P4HTM

Item number: G-CAB13593.100

IF 1:50 - 1:200. Protein function: Catalyzes the post-translational formation of 4- hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for...
Keywords: Anti-PH4, Anti-HPH-4, Anti-P4HTM, Anti-P4H-TM, Anti-HIF-PH4, Anti-HIF-prolyl hydroxylase 4, Anti-Transmembrane prolyl...
Application: IF
Host: Rabbit
Species reactivity: human
From 352.00€ *
Review
Anti-P4HTM
Anti-P4HTM

Item number: G-CAB6143.100

Application: WB
Host: Rabbit
Species reactivity: human, mouse
From 352.00€ *
Review
Anti-P4HTM
Anti-P4HTM

Item number: ATA-HPA007199.100

Protein function: Catalyzes the post-translational formation of 4- hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal...
Keywords: Anti-PH4, Anti-HPH-4, Anti-P4HTM, Anti-P4H-TM, Anti-HIF-PH4, Anti-HIF-prolyl hydroxylase 4, Anti-Transmembrane prolyl...
Application: IHC, WB
Host: Rabbit
Species reactivity: human
446.00€ *
Review
-10 %
Discount Promotion
Human P4HTM (Transmembrane prolyl 4-hydroxylase) ELISA Kit
Human P4HTM (Transmembrane prolyl 4-hydroxylase) ELISA Kit

Item number: ELK-ELK9846.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human P4HTM. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human P4HTM. Next,...
Keywords: PH4, P4HTM, HPH-4, P4H-TM, HIF-PH4, HIF-prolyl hydroxylase 4, Transmembrane prolyl 4-hydroxylase, Hypoxia-inducible factor...
Application: ELISA
Species reactivity: human
470.00€ * From 423.00€ *
Review
1,4-DPCA
1,4-DPCA

Item number: LKT-D6108.25

Prolyl hydroxylase inhibitor.
Keywords: 1,4-Dihydrophenonthrolin-4-one-3-carboxylic acid, 3-Acetyl-1H-[1,10]phenanthrolin-4-one,...
Application: Prolyl hydroxylase inhibitor
CAS 331830-20-7
MW: 240.22 D
From 72.00€ *
Review
P4HTM, Recombinant, Human, aa82-563, His-SUMO-Tag (Transmembrane Prolyl 4-hydroxylase)
P4HTM, Recombinant, Human, aa82-563, His-SUMO-Tag...

Item number: 374590.100

Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von...
Keywords: PH4, HPH-4, P4HTM, P4H-TM, HIF-PH4, HIF-prolyl hydroxylase 4, Transmembrane prolyl 4-hydroxylase, Hypoxia-inducible factor...
MW: 70,5
From 511.00€ *
Review
P4HTM PrEST Antigen
P4HTM PrEST Antigen

Item number: ATA-APrEST71314.100

Protein function: Catalyzes the post-translational formation of 4- hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal...
Keywords: PH4, HPH-4, P4HTM, P4H-TM, HIF-PH4, HIF-prolyl hydroxylase 4, Transmembrane prolyl 4-hydroxylase, Hypoxia-inducible factor...
Application: Control antigen
Expressed in: E.coli
Origin: human
247.00€ *
Review
1 from 2 pages