85 products were found matching "K06487"!

alphavbeta5 Integrin-IN-1 is an inhibitor of alphaVbeta5 integrin (IC50 = 0.0063 µM). It is selective for alphaVbeta5 over alphaVbeta1, alphaVbeta3, alphaVbeta6, and alphaVbeta8 (IC50s = 2.51, 5.01, 50.1, and 50.1 µM, respectively). alphavbeta5 Integrin-IN-1 inhibits adhesion of alphaVbeta5-expressing K562 cells to...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Integrin alpha-V / CD51 is a protein that in humans is encoded by the ITGAV gene. It is a member of the beta 3 integrin subfamily(cytoadhesins). The human locus for the av gene (VNRA) was previously mapped to the long arm of chromosome 2. Sims et al.(2000)...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ITGaV. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ITGaV. Next,...

CD51 is a 140 kD protein, also known as alphaV integrin, vitronectin receptor, and integrin alphaV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins beta1, beta3, beta5...

CD51 is a 140 kD protein, also known as alphaV integrin, vitronectin receptor, and integrin alphaV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins beta1, beta3, beta5...

CD51 is a 140 kD protein, also known as alphaV integrin, vitronectin receptor, and integrin alphaV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins beta1, beta3, beta5...

CD51 is a 140 kD protein, also known as alphaV integrin, vitronectin receptor, and integrin alphaV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins beta1, beta3, beta5...

CD51 is a 140 kD protein, also known as alphaV integrin, vitronectin receptor, and integrin alphaV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins beta1, beta3, beta5...

CD51 is a 140 kD protein, also known as alphaV integrin, vitronectin receptor, and integrin alphaV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins beta1, beta3, beta5...

CWHM12 is an analog of RGD peptide (Cay-14501), a tripeptide that inhibits integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation. CWHM12 selectively inhibits alphav integrins (IC50s = 1.8, 0.8, 61, 1.5, and 0.2 nM for alphavbeta1, alphavbeta3, alphavbeta5,...

Cilengitide is a cyclo-(Arg-Gly-Asp-D-Phe-Val) (cRGDfV) peptide and integrin alphaVbeta3 receptor antagonist. It inhibits adhesion and induces apoptosis of U87MG and U373MG malignant glioma (MG) cells, but not U251MG cells that lack the integrin alphaVbeta3 receptor, in vitro at a concentration of 20 µg/ml....

GLPG0187 is a nonpeptide antagonist of alphanu integrin receptors (IC50s = 1.2-3.7 nM). It inhibits osteoclastogenesis, bone resorption, and angiogenesis in vitro and in vivo in mice, which are all hallmarks of bone marrow invasion in metastatic prostate cancer. GLPG0187 reduces epithelial-mesenchymal transition...