26 products were found matching "K04995"!

KCNJ1 (Kir1.1, or renal outer medullary potassium channel) and KCNJ13 (Kir7.1) are inwardly rectifying two-transmembrane K+ channels. KCNJ1 has critical roles in kidney function, while KCNJ13 is important in the eye, kidney, and small intestine. VU590 is a small molecule inhibitor of KCNJ1 (IC50 = 294 nM) which also...

Protein function: In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Potassium inwardly-rectifying channel, subfamily J, member 1 Protein function: In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are...

Protein function: In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as...

Tertiapin LQ is a peptide derivative of the honeybee venom peptide tertiapin and an inhibitor of inwardly rectifying potassium (Kir) channels. It inhibits heteromultimeric potassium channels composed of G protein-activated inward rectifier potassium channel 1 (GIRK1) and GIRK4, also known as Kir3.1 and Kir3.4,...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 178-391aa. Protein Length: Cytoplasmic Domain. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: ILAKISRPKK RAKTITFSKN AVISKRGGKL CLLIRVANLR KSLLIGSHIY GKLLKTTVTP EGETIILDQI NINFVVDAGN ENLFFISPLT IYHVIDHNSP FFHMAAETLL QQDFELVVFL DGTVESTSAT...

Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 178-391aa. Protein Length: Cytoplasmic Domain. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: ILAKISRPKK RAKTITFSKN AVISKRGGKL CLLIRVANLR KSLLIGSHIY GKLLKTTVTP EGETIILDQI NINFVVDAGN ENLFFISPLT IYHVIDHNSP FFHMAAETLL QQDFELVVFL DGTVESTSAT...

Description: VU590 is a small molecule inhibitor of KCNJ1 (IC50 = 294 nM). Target: Others. Smiles: O=[N+]([O-])C(C=C1)=CC=C1CN(CCOCC2)CCOCCOCCN2CC(C=C3)=CC=C3[N+]([O-])=O.Cl.Cl

Protein function: In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as...

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP...

In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of Extracellular domain potassium, as external...