46 products were found matching "K04858"!

Description: Mirogabalin (DS5565) is a calcium channel blocker with analgesic effects. Target: Calcium Channel. Smiles: CCC1=C[C@@H]2[C@@H](C[C@]2(CN)CC(O)=O)C1. References: Vinik A , Rosenstock J , Sharma U , et al. Efficacy and Safety of Mirogabalin (DS-5565) for the Treatment of Diabetic Peripheral Neuropathic...

gamma-Aminobutyric acid (GABA) is a major inhibitory neurotransmitter that functions by binding to the GABA receptors located in the spinal cord. Gabapentin is a gamma-aminobutyric acid (GABA) analogue that acts as an anticonvulsant with proven analgesic effects in various neuropathic pain syndromes such as Complex...

Gabapentin-d4 is intended for use as an internal standard for the quantification of gabapentin (Cay-10008346) by GC- or LC-MS. Gabapentin is a gamma-aminobutyric acid (GABA) analogue that acts as an anticonvulsant. It does not bind to GABA receptors, does not influence neural uptake of GABA, and does not inhibit the...

Protein function: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling. [The UniProt Consortium]

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Calcium channel, voltage-dependent, alpha 2/delta subunit 1 Protein function: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and...

Protein function: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation- contraction coupling. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium...

Protein function: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation- contraction coupling. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium...

(±)-Pregabalin-13C3 (Cay-33879) is intended for use as an internal standard for the quantification for pregabalin (Cay-13663) by GC- or LC-MS. Pregabalin is categorized as an anticonvulsant and analgesic. It has potential for abuse and misuse. (±)-Pregabalin-13C3 is regulated as a Schedule V compound in the United...

Gabapentin (CRM) (Cay-37860) is a certified reference material categorized as an anticonvulsant and analgesic. This product is intended for analytical forensic applications. This product is also available as a general research tool (Cay-10008346).Formal Name: 1-(aminomethyl)-cyclohexaneacetic acid. CAS Number:...

Pregabalin (CRM) (Cay-37861) is a certified reference material categorized as an anticonvulsant and analgesic. Pregabalin has a potential for abuse and misuse. Pregabalin is regulated as a Schedule V compound in the United States. This product is intended for research and forensic applications.Formal Name:...

Voltage-gated Ca2+ channels (CaV), enable the passage of Ca2+ ions in a voltage dependent manner. These heteromeric entities are formed in part by the pore-forming alpha1 subunit which determines the biophysical and pharmacological properties of the channel. Protein function: The alpha-2/delta subunit of...

NP-118809 is an inhibitor of N-type voltage-gated calcium channels (IC50 = 0.11 µM). It is selective for N-type over L-type voltage-gated calcium channels and human-ether-a-go-go (hERG), also known as Kv11.1 (IC50s = 12.2 and 7.4 µM, respectively), as well as a panel of 112 other ion channels, receptors, and...