210 products were found matching "K04440"!

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Human MAPK9 (Mitogen Activated Protein Kinase 9) ELISA Kit
Human MAPK9 (Mitogen Activated Protein Kinase 9) ELISA Kit

Item number: ELK-ELK5554.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MAPK9. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MAPK9. Next,...
Keywords: JNK2, MAPK9, JNK-55, SAPK1a, MAPK 9, MAP kinase 9, c-Jun N-terminal kinase 2, Mitogen-activated protein kinase 9,...
Application: ELISA
Species reactivity: human
365.00€ * From 328.50€ *
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Human JNK (c-Jun N-terminal kinases) ELISA Kit
Human JNK (c-Jun N-terminal kinases) ELISA Kit

Item number: ELK-ELK0663.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human JNK. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human JNK. Next,...
Keywords: MAPK8, MAPK 8, JNK-46, SAPK1c, MAP kinase 8, c-Jun N-terminal kinase 1, Stress-activated protein kinase 1c,...
Application: ELISA
Species reactivity: human
365.00€ * From 328.50€ *
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Anti-JNK2
Anti-JNK2

Item number: ELK-EA342.100

There are three SAPK/JNK genes each of which undergoes alternative splicing, resulting in numerous isoforms. SAPK/JNK, when active as a dimer, can translocate to the nucleus and regulate transcription through its effects on c-Jun, ATF-2, and other transcription factors. Protein function: Serine/threonine-protein...
Keywords: Anti-JNK2, Anti-MAPK9, Anti-SAPK1a, Anti-JNK-55, Anti-MAPK 9, Anti-MAP kinase 9, Anti-c-Jun N-terminal kinase 2,...
Application: WB, IHC
Host: Rabbit
Species reactivity: human
283.00€ * 254.70€ *
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Anti-JNK3
Anti-JNK3

Item number: ELK-EA343.50

There are three SAPK/JNK genes each of which undergoes alternative splicing, resulting in numerous isoforms. SAPK/JNK, when active as a dimer, can translocate to the nucleus and regulate transcription through its effects on c-Jun, ATF-2, and other transcription factors. Protein function: Serine/threonine-protein...
Keywords: Anti-JNK3, Anti-SAPK1b, Anti-MAPK10, Anti-MAPK 10, EC=2.7.11.24, Anti-MAP kinase 10, Anti-MAP kinase p49 3F12, Anti-c-Jun...
Application: IHC
Host: Rabbit
Species reactivity: human
169.00€ * 152.10€ *
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SP 600125
SP 600125

Item number: Cay10010466-10

SP6000125 is a pan-inhibitor of JNK (IC50s = 0.04, 0.04, and 0.09 µM for JNK1, -2, and -3, respectively). It is greater than 300-fold selective for these enzymes over a panel of 17 additional kinases at 10 µM. SP6000125 reduces LPS-induced production of IL-1beta, IL-8, and TNF-alpha in isolated human peripheral...
Keywords: 1PMV, NSC 75890, Pyrazolanthrone, anthra[1,9-cd]pyrazol-6(2H)-one
Application: JNK inhibitor
CAS 129-56-6
MW: 220.2 D
From 60.00€ *
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Anti-SAPK1 / JNK1
Anti-SAPK1 / JNK1

Item number: ARG43819.100

Protein function: Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress- activated protein kinase/c-Jun N-terminal...
Keywords: Anti-JNK1, Anti-MAPK8, Anti-MAPK 8, Anti-JNK-46, Anti-SAPK1c, Anti-MAPK 8, Anti-JNK-46, Anti-SAPK1c, Anti-MAP kinase 8,...
Application: IP, WB
Host: Rabbit
Species reactivity: human, mouse, rat, hamster
624.00€ *
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SP600125
SP600125

Item number: AG-CR1-3549-M001

SP600125 is an orally active, reversible and ATP-competitive broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 (IC50 = 40nM, 40nM and 90nM, respectively). In Jurkat T cells, SP600125 suppressed the phosphorylation of c-Jun with IC50 of 5-10 µM. It has 10-fold greater selectivity against MKK4, 25-fold greater...
Keywords: Anthra[1-9-cd]pyrazol-6(2H)-one, 1,9-Pyrazoloanthrone, Pyrazolanthrone, NSC 75890
Application: Reversible, ATP-competitive JNK1/JNK2/JNK3 inhibitor
CAS 129-56-6
MW: 220,2 D
22.00€ * From 19.80€ *
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Anti-Phosphorylated JNK / pThr183/pTyr185, clone RM464
Anti-Phosphorylated JNK / pThr183/pTyr185, clone RM464

Item number: NSJ-R20476-0.1ML

Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. Protein function: Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical...
Keywords: Anti-phospho-JNK1, Anti-phospho-MAPK8, Anti-phospho-JNK-46, Anti-phospho-MAPK 8, Anti-phospho-SAPK1c, Anti-phospho-MAP...
Application: WB, IHC (paraffin)
Host: Rabbit
Species reactivity: human
737.00€ *
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JNK Inhibitor VIII
JNK Inhibitor VIII

Item number: Cay15946-5

JNK inhibitor VIII is an inhibitor of JNK1, JNK2, and JNK3 (Kis= 2, 4, and 52 nM, respectively). It is selective for JNK1, JNK2, and JNK3 over a panel of 74 kinases (Kis = >720 nM for all). It inhibits the phosphorylation of c-Jun in HepG2 cells (EC50 = 920 nM). JNK inhibitor VIII (10 µM) inhibits NGF-induced...
Keywords: c-Jun N-terminal Kinase Inhibitor VIII, TCS JNK 6o, N-(4-amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxy-benzeneacetamide
Application: JNK1 / JNK2 / JNK3 inhibitor
CAS 894804-07-0
MW: 356.4 D
From 135.00€ *
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CC-930
CC-930

Item number: Cay22466-1

CC-930 is an orally bioavailable and potent inhibitor of JNKs (IC50s = 61, 7, and 6 nM for JNK1, JNK2, and JNK3, respectively). It is selective for MAP kinases over a panel of 240 kinases, showing greater than 50% inhibition at only one non-MAP kinase target, EGFR (IC50 = 380 nM). Within the MAPK family, it is...
Keywords: Tanzisertib, trans-4-[[9-[(3S)-tetrahydro-3-furanyl]-8-[(2,4,6-trifluorophenyl)amino]-9H-purin-2-yl]amino]-cyclohexanol
Application: JNK inhibitor
CAS 899805-25-5
MW: 448.4 D
From 48.00€ *
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CC-401
CC-401

Item number: Cay18867-1

c-Jun N-terminal kinases (JNKs) are MAP kinase family members that become highly activated after cells are exposed to stress conditions and are poorly activated by exposure to growth factors or mitogens. CC-401 is a potent inhibitor of all three JNK isoforms (Ki values range from 25 to 50 nM). It has at least...
Keywords: 3-[3-[2-(1-piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole
Application: JNK inhibitor
CAS 395104-30-0
MW: 388.5 D
From 142.00€ *
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Bentamapimod
Bentamapimod

Item number: Cay21482-1

Bentamapimod is an orally bioavailable inhibitor of Jun kinases (JNKs), with IC50 values for JNK1, JNK2, and JNK3 of 80, 90, and 230 nM, respectively. It is selective for JNKs over a panel of 25 related kinases. Bentamapimod induces regression of endometriotic lesions without suppressing estrogen action in animal...
Keywords: AS-602801, alpha-[2-[[4-(4-morpholinylmethyl)phenyl]methoxy]-4-pyrimidinyl]-2-benzothiazoleacetonitrile
Application: JNK1 / JNK2 / JNK3 inhibitor
CAS 848344-36-5
MW: 457.5 D
From 54.00€ *
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