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TAS 205
TAS 205

Item number: Cay33261-1

TAS 205 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS, IC50 = 55.8 nM). It is selective for H-PGDS over lipocalin-type PGDS (L-PGDS) at 100 µM, as well as over enzyme and receptor panels at 10 µM. TAS 205 inhibits production of prostaglandin D2 (PGD2, Cay-12010) induced by A23187 (Cay-11016) in...
Keywords: 4-[(1-methyl-1H-pyrrol-2-yl)carbonyl]-N-[4-[4-(4-morpholinylcarbonyl)-1-piperidinyl]phenyl]-1-piperazinecarboxamide,...
Application: H-PGDS inhibitor
CAS 1584160-52-0
MW: 526.6 D
From 87.00€ *
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Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092
Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092

Item number: Cay28721-1

Prostaglandin D synthase (hematopoietic-type) inhibitor F092 is an inhibitor of hematopoietic-type prostaglandin D synthase (H-PGDS, KD = 0.14 nM). Formal Name: N-[4-(2-oxo-1-pyrrolidinyl)phenyl]-2-(2-pyridinyl)-5-pyrimidinecarboxamide. CAS Number: 2250261-59-5. Molecular Formula: C20H17N5O2. Formula Weight: 359.4....
Keywords: N-[4-(2-oxo-1-pyrrolidinyl)phenyl]-2-(2-pyridinyl)-5-pyrimidinecarboxamide
Application: Hematopoietic prostaglandin D synthase (H-PGDS) inhibitor
CAS 2250261-59-5
MW: 359.4 D
From 62.00€ *
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Anti-Prostaglandin D Synthase (hematopoietic-type)
Anti-Prostaglandin D Synthase (hematopoietic-type)

Item number: Cay160013-1

Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGDS have been identified, namely the lipocalin type enzyme (beta-trace) and the hematopoietic enzyme....
Keywords: Anti-GSTS, Anti-H-PGDS, Anti-H-PGDS, Anti-GST class-sigma, Anti-GST class-sigma, Anti-Glutathione S-transferase,...
Application: WB
324.00€ *
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Human PGDS (Prostaglandin D Synthase) CLIA Kit
Human PGDS (Prostaglandin D Synthase) CLIA Kit

Item number: G-HUES01016.96

ELISA Type: CLIA. Sensitivity: 9.375 pg/mL. Range: 15.625--1000 pg/mL. Protein function: Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a...
Keywords: GSTS, HPGDS, H-PGDS, GST class-sigma, Glutathione S-transferase, Prostaglandin-H2 D-isomerase, Glutathione-dependent PGD...
Application: CLIA
Reactivity: Human
629.00€ *
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Human PGDS (Prostaglandin D Synthase) ELISA Kit
Human PGDS (Prostaglandin D Synthase) ELISA Kit

Item number: G-HUES02792.96

ELISA Type: Sandwich. Sensitivity: 46.875pg/mL. Range: 78.125--5000pg/mL. Protein function: Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with...
Keywords: GSTS, HPGDS, H-PGDS, GST class-sigma, Glutathione S-transferase, Prostaglandin-H2 D-isomerase, Glutathione-dependent PGD...
Application: Sandwich ELISA
Reactivity: Human
566.00€ *
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Prostaglandin D Synthase (hematopoietic-type) FP-Based Inhibitor Screening Assay Kit - Green
Prostaglandin D Synthase (hematopoietic-type) FP-Based...

Item number: Cay600007-1920

Prostaglandin D2 (PGD2) is synthesized by hematopoietic-type PGD-synthase (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. H-PGDS is therefore a key target for development of selective, potent inhibitors for therapeutic use against these diseases. Cayman's H-PGDS...
Keywords: H-PGDS FP-Based Inhibitor Screening Assay Kit - Green, Prostaglandin D Synthase (hematopoietic-type) Fluorescence...
Application: PGDS inhibitor screening
From 445.00€ *
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Anti-Prostaglandin D Synthase
Anti-Prostaglandin D Synthase

Item number: ARG56489.250

Protein function: Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits...
Keywords: Anti-GSTS, Anti-HPGDS, Anti-H-PGDS, Anti-GST class-sigma, Anti-Glutathione S-transferase, Anti-Prostaglandin-H2...
Application: WB
Reactivity: Human, Mouse, Rat, Baboon
483.00€ *
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Prostaglandin D Synthase (hematopoietic-type, human recombinant)
Prostaglandin D Synthase (hematopoietic-type, human...

Item number: Cay10006593-100

Prostaglandin D synthase (PGD synthase) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGD synthase have been identified, namely the lipocalin-type enzyme (beta-trace) and the...
Keywords: H-PGDS, Hematopoietic-PGDS, hH-PGDS, PGD Synthase (hematopoietic-type, human recombinant)
Application: Enzyme activity
MW: 23,3 kD
394.00€ *
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Hematopoietic Prostaglandin D Synthase/HPGDS/GSTS Protein (recombinant human)
Hematopoietic Prostaglandin D Synthase/HPGDS/GSTS Protein...

Item number: E-PKSH032528.10

Protein Construction: Recombinant Human Hematopoietic Prostaglandin D Synthase is produced by our E.coli expression system and the target gene encoding Met1-Leu199 is expressed. Sequence: Met 1-Leu199. Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 26 kDa. Protein function:...
Keywords: GSTS, HPGDS, H-PGDS, GST class-sigma, Glutathione S-transferase, Prostaglandin-H2 D-isomerase, Glutathione-dependent PGD...
Reactivity: Human
MW: 23.6 kD
From 358.00€ *
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PGDS (Prostaglandin D Synthase) BioAssay(TM) ELISA Kit (Human)
PGDS (Prostaglandin D Synthase) BioAssay(TM) ELISA Kit...

Item number: 384044.96

Sample Type:, Serum, Plasma, Biological Fluids, Intended Use: This BioAssay(TM) kit is a sandwich ELISA for in vitro quantitative measurement of PGDS in human serum, plasma and other biological fluids, Sensitivity: 46.875pg/mL, Range: 78.125-5000pg/mL, Specificity: Human, Test Principle: This BioAssay(TM) ELISA kit...
Keywords: GSTS, H-PGDS, GST class-sigma, Glutathione S-transferase, Prostaglandin-H2 D-isomerase, Glutathione-dependent PGD...
Application: ELISA
Reactivity: Human
714.00€ *
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Anti-Prostaglandin D Synthase (hematopoietic-type, human) (Clone 2A5)
Anti-Prostaglandin D Synthase (hematopoietic-type, human)...

Item number: Cay10004345-1

Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation and acts as an allergic mediator. Two distinct types of PGDS have been identified, namely the lipocalin-type enzyme (beta-trace) and the hematopoietic enzyme....
Keywords: H-PGD Synthase, H-PGDS
Application: IHC, WB
Reactivity: Human, Mouse
324.00€ *
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Anti-Prostaglandin D Synthase (hematopoietic-type, mouse)
Anti-Prostaglandin D Synthase (hematopoietic-type, mouse)

Item number: Cay10004349-1

Prostaglandin D synthase (PGDS) is a glutathione-dependent enzyme and member of the sigma class of glutathione-S-transferases (GSTs) that catalyzes the conversion of PGH2 (Cay-17020) to PGD2 (Cay-12010), an eicosanoid that has numerous biological functions, including vasorelaxation, recruitment of inflammatory...
Keywords: Anti-Gsts, Anti-H-PGDS, Anti-H-PGDS, Anti-GST class-sigma, Anti-GST class-sigma, Anti-Glutathione S-transferase,...
Application: IHC, WB
Reactivity: Mouse
324.00€ *
Review
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