105 products were found matching "K01348"!

The urokinase-type plasminogen activator (uPA, PLAU) converts plasminogen to plasmin. Plasmin is involved in the processing of amyloid precursor protein and degrades secreted and aggregated amyloid-beta, a hallmark of Alzheimer's disease (AD). Urokinase has a molecular mass of about 54 kDa and is composed of 2...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human uPA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human uPA. Next,...

Description: PLAU/uPA Protein, Human, Recombinant (His) is expressed in HEK293 Cells with C-10xHis. The accession number is P00749.

Description: Urokinase/uPA Protein, Human, Recombinant (Activated, His) is expressed in HEK293 Cells. The accession number is P00749-1.

Urokinase-type plasminogen activator (uPA) is a serine protease that converts enzymatically inactive plasminogen into active plasmin. It is synthesized and released as a single polypeptide chain called pro-uPA, which contains three domains: a growth factor domain (GFD), a kringle domain, and a serine protease...

An inhibitor of uPA (IC50 = 0.32 µM), selective for uPA over tPA and plasmin (IC50s = 107 and 352 µM, respectively), cytotoxic to F3II mouse breast cancer cells (IC50 = 18 µM), inhibits muscle and adipose tissue invasion in an F3II murine breast cancer model at 20 mg/kg per day, decreases ethanol consumption and...

6-Aminocaproic acid is an inhibitor of the plasmin activating enzymes streptokinase, fibrinokinase, and urokinase (IC50s = ~8 µM for all in an enzyme assay). It is selective for plasmin activating enzymes over trypsin (IC50 = >500 µM). 6-Aminocaproic acid inhibits in vitro plasmin activation and fibrinolysis in a...

Gabexate is a competitive inhibitor of serine proteases that inhibits human thrombin, urokinase, plasmin, and Factor Xa (Kis = 0.97, 1.3, 1.6, and 8.5 µM, respectively)., It also inhibits bovine thrombin, Factor Xa, and trypsin, and porcine plasma kallikrein (Kis = 1.4, 2.1, 2.6, and 0.2 µM, respectively)., In...

Protein function: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. [The UniProt Consortium]

Natural and recombinant human Upa. There is no detectable cross-reactivity with other relevant proteins. Protein function: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. [The UniProt Consortium]