53 products were found matching "K00796"!

Sulfamethoxazole is a sulfonamide antibiotic. It inhibits growth of E. coli (MIC = 10 µg/ml) and clinical isolates of methicillin-resistant S. aureus (MRSA, MICs = 25-50 µg/ml). Sulfamethoxazole, in combination with trimethoprim (Cay-16473) at a ratio of 20:1, inhibits growth of MRSA in vivo in mice (MIC = 0.8...

Sulfamethazine is a sulfonamide antibiotic. It inhibits dihydropteroate synthase (DHPS, IC50 = 5.7 µM for the T. gondii enzyme). Sulfamethazine is active against A. pleuropneumoniae (MIC = 32 µg/ml) and enhances the antibacterial activity of trimethoprim (Cay-16473) against E. coli. It has been detected in...

Sulfamethoxazole-d4 is intended for use as an internal standard for the quantification of sulfamethoxazole (Cay-23613) by GC- or LC-MS. Sulfamethoxazole is a sulfonamide antibiotic. It inhibits growth of E. coli (MIC = 10 µg/ml) and clinical isolates of methicillin-resistant S. aureus (MRSA, MICs = 25-50 µg/ml)....

Sulfacetamide is a sulfonamide antibiotic that is bacteriostatic against Gram-positive and Gram-negative bacteria. It inhibits dihydropteroate synthase (IC50 = 9.6 µM), blocking the synthesis of dihydrofolic acid, and also inhibits bacterial 4-aminobenzoic acid (Cay-18659), which is required for the synthesis of...

Off-white powder. Soluble in methanol or DMSO. Sligthly soluble in water. Metabolite of sulfamethoxazole, a sulfonamide bacteriostatic antibiotic. Has been shown to be an important component in sulfonamide hypersensitivity reactions and has been implicated in sulfonamide-mediated immunomodulatory effects. Shown to...

Sulfamethoxypyridazine is a sulfonamide antibiotic that inhibits the growth of Gram-negative bacteria and other microorganisms. It inhibits recombinant P. carinii dihydropteroate synthase (DHPS, IC50 = 17 nM) and folate biosynthesis in P. carinii by 75% when used at a concentration of 50 nM. Sulfamethoxypyridazine...

Sulfameter is a long-acting sulfonamide antibiotic. In vitro, it is active against the bacteria D. pneumoniae, K. pneumoniae, E. coli, N. meningitidis, P. vulgaris, S. aureus, S. haemolyticus, and S. typhimurium in a disc assay. Sulfameter is efficacious against lethal K. pneumoniae, E. coli, P. vulgaris, D....

Sulfadimethoxine is a sulfonamide antibiotic that is active against Gram-negative and Gram-positive bacteria and other microorganisms. It inhibits recombinant P. carinii dihydropteroate synthase (DHPS, IC50 = 25 nM), an enzyme required for folate biosynthesis, in a cell-free assay. Sulfadimethoxine is active against...

Description: Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 µM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 µM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19). At 10 µM, sulfaphenazole has been shown to inhibit...

Sulfanilamide is a sulfonamide antibiotic. It is bacteriostatic against Streptococcus when used at a concentration of 20 µg/ml and inhibits the growth of 106 clinical isolates of Gonococcus at 0.01% v/v. Sulfanilamide reduces plasma levels of Streptococcus in infected rabbits. It is an inhibitor of carbonic...

Dapsone is an anti-inflammatory, antimalarial, and antibacterial compound. In vivo, dapsone (34 µg/animal per day) reduces epidermal hyperproliferation and epithelial thickness in the esophagus in a mouse model of proliferative dermatitis. It reduces lipid peroxidation, myeloperoxidase activity, and cellular...

Sulfadoxin is a sulfonamide antibiotic that inhibits dihydropteroate synthetase (DHPS), an enzyme involved in folic acid (Cay-20515) synthesis. Sulfadoxin competes with 4-aminobenzoate (PABA), the native substrate of DHPS, and inhibits PABA incorporation into folic acid. Folate is essential for purine and pyrimidine...