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Ponatinib
Ponatinib

Item number: Cay11494-1

Ponatinib is an orally bioavailable Bcr-Abl tyrosine kinase inhibitor (IC50 = 0.37 nM). It inhibits the tyrosine kinase inhibitor-resistant mutant Bcr-AblT315I (IC50 = 2 nM), as well as Bcr-AblQ252H, Bcr-AblY253F, Bcr-AblM351T, and Bcr-AblH396P mutants (IC50s = 0.44, 0.3, 0.3, and 0.34 nM, respectively). It is...
Keywords: AP 24534,...
Application: Bcr-Abl tyrosine kinase inhibitor
CAS 943319-70-8
MW: 532.6 D
From 39.00€ *
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Ponatinib
Ponatinib

Item number: AG-CR1-3538-M001

Pale yellow solid. Soluble in DMSO (30mg/ml), DMF (30mg/ml) or ethanol (5mg/ml). Chemical CAS: 943319-70-8. Formula: C29H27F3N6O. MW: 532.6. Ponatinib is a potent multi-target kinase inhibitor with antiangiogenic and antineoplastic activities. It targets protein tyrosine kinases (PTK), which catalyze the transfer of...
Keywords: AP 24534, AP-24534
Application: Antineoplastic, BCR-ABL tyrosine kinase inhibitor
CAS 943319-70-8
MW: 532.6 D
From 28.00€ *
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Ponatinib
Ponatinib

Item number: LKT-P577520.100

pan-Bcr-Abl tyrosine kinase inhibitor.
Keywords: AP-24534, AP 24534, AP24534, Iclusig
Application: c-Src tyrosine kinase inhibitor, Bcr-Abl tyrosine kinase inhibitor
CAS 943319-70-8
MW: 532.57 D
From 117.00€ *
Review