4 products were found matching "943319-70-8"!
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Ponatinib
Item number: Cay11494-1
Ponatinib is an orally bioavailable Bcr-Abl tyrosine kinase inhibitor (IC50 = 0.37 nM). It inhibits the tyrosine kinase inhibitor-resistant mutant Bcr-AblT315I (IC50 = 2 nM), as well as Bcr-AblQ252H, Bcr-AblY253F, Bcr-AblM351T, and Bcr-AblH396P mutants (IC50s = 0.44, 0.3, 0.3, and 0.34 nM, respectively). It is...
| Keywords: | AP 24534,... |
| Application: | Bcr-Abl tyrosine kinase inhibitor |
| CAS | 943319-70-8 |
| MW: | 532.6 D |
From 45.00€
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Ponatinib
Item number: AG-CR1-3538-M001
Pale yellow solid. Soluble in DMSO (30mg/ml), DMF (30mg/ml) or ethanol (5mg/ml). Chemical CAS: 943319-70-8. Formula: C29H27F3N6O. MW: 532.6. Ponatinib is a potent multi-target kinase inhibitor with antiangiogenic and antineoplastic activities. It targets protein tyrosine kinases (PTK), which catalyze the transfer of...
| Keywords: | AP 24534, AP-24534 |
| Application: | Antineoplastic, BCR-ABL tyrosine kinase inhibitor |
| CAS | 943319-70-8 |
| MW: | 532.6 D |
From 28.00€
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Ponatinib
Item number: LKT-P577520.100
pan-Bcr-Abl tyrosine kinase inhibitor.
| Keywords: | AP-24534, AP 24534, AP24534, Iclusig |
| Application: | c-Src tyrosine kinase inhibitor, Bcr-Abl tyrosine kinase inhibitor |
| CAS | 943319-70-8 |
| MW: | 532.57 D |
From 123.00€
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Ponatinib
Item number: TGM-T2372-100mg
Description: Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor with IC50 values of 0.37 nM (Abl), 1.1 nM (PDGFRalpha), 1.5 nM (VEGFR2), 2.2 nM (FGFR1), and 5.4 nM (Src). Target: PDGFR, Bcr-Abl, Autophagy, Src, VEGFR, c-Kit, FGFR. Smiles:...
| Keywords: | AP24534 |
| CAS | 943319-70-8 |
| MW: | 532.56 D |
From 34.00€
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