2 products were found matching "908568-01-4"!

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Item number: Cay17006-10

Inflachromene is an anti-inflammatory agent that directly binds high mobility group protein 1 (HMGB1) and HMGB2 and reduces their cytoplasmic accumulation in microglial cells. It is functional in vivo, downregulating proinflammatory functions of HMGB proteins and reducing neuronal damage. Inflachromene also...

Keywords:	ICM, 5,12b-dihydro-10-hydroxy-7,7-dimethyl-2-phenyl-1H,7H-[1]benzopyrano[4,3-c][1,2,4]triazolo[1,2-a]pyridazine-1,3(2H)-dione
Application:	Microglial inhibitor
CAS	908568-01-4
MW:	377.4 D

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Inflachromene

Item number: TGM-T24167-100mg

Description: Inflachromene (ICM) is an inhibitor of HMGB1 and HMGB expression with anti-inflammatory activity.Inflachromene reduces seizure severity in a mouse model of epilepsy by inhibiting HMGB1 translocation, inhibits endothelial proliferation through the HMGB1/2-regulated TLR4-NF-kappaB pathway, and inhibits...

Keywords:	ICM
CAS	908568-01-4
MW:	377.39 D

From 110.00€ *

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