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Item number: Cay33224-10

Cevipabulin is an activator of microtubule polymerization. It induces aggregation of isolated bovine brain tubulin in a concentration-dependent manner. Cevipabulin (100 µM) inhibits binding of vinblastine (Cay-11762), but not colchicine (Cay-9000760), to tubulin in cell-free assays. It induces mitotic block in HeLa...

Keywords:	TTI-237,...
Application:	Microtubule polymerization activator, antineoplastic
CAS	849550-05-6
MW:	464.8 D

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Cevipabulin

Item number: TGM-T10772-10mg

Description: Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell line). Target: Microtubule Associated. Smiles: [H][C@@](C)(Nc1c(c(Cl)nc2ncnn12)-c1c(F)cc(OCCCNC)cc1F)C(F)(F)F. References: Beyer CF, et al....

Keywords:	TTI-237
CAS	849550-05-6
MW:	464.82 D

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