Propentofylline is a xanthine derivative and neuroprotective agent. It increases NGF production in primary mouse astroglia when used at concentrations ranging from 0.12 to 3.33 mM, with the maximum increase observed at 1.11 mM. Propentofylline (20 µg/ml) reduces cell death induced by amyloid-beta (1-42) (Abeta42,...

Description: Propentofylline (Hextol) is a methylxanthine derivative with neuroprotective, antiproliferative, and anti-inflammatory activity and enhanced synaptic adenosine signaling, which may be useful in the study of Alzheimer's disease, vascular dementia, cognitive impairment, dementia, and chronic pain. Target:...