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Item number: TGM-T2027-5mg

Description: ISRIB is a potent and selective PERK inhibitor. Target: PERK. Smiles: Clc1ccc(OCC(=O)NC2CCC(CC2)NC(=O)COc2ccc(Cl)cc2)cc1. References: Sidrauski C, et al. Elife. 2013, 2, e00498.

CAS	548470-11-7
MW:	451.34 D

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ISRIB

Item number: Cay41879-10

A mixture of cis-IRIB and trans-ISRIB, trans-ISRIB decreases ATF4-induced increases in gene transcription more effectively than cis-ISRIB in a reporter assay using HEK293T cells (IC50s = 5 and 600 nM, respectively), trans-ISRIB decreases the latency to escape in the Morris water maze and increases the length of...

Keywords:	N,N'-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)-acetamide
Application:	Cis-IRIB / trans-ISRIB mixture
CAS	548470-11-7
MW:	451.3 D

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