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17-DMAG
Item number: Cay11036-1
Geldanamycin (Cay-13355) is a potent inhibitor of Hsp90 that has poor water solubility. 17-DMAG is a water-soluble derivative of geldanamycin which potently inhibits Hsp90 (IC50 = 24 nM) and has excellent bioavailability and tissue distribution in animals. Like other Hsp90 inhibitors, 17-DMAG has diverse anti-tumor...
| Keywords: | Alvespimycin, KOS-1022, NSC 707545, 17-demethoxy-17-[[2-(dimethylamino)ethyl]amino]-geldanamycin |
| Application: | Hsp90 inhibitor |
| CAS | 467214-20-6 |
| MW: | 616.8 D |
From 56.00€
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17-DMAG
Item number: LKT-D4802.5
A novel heat shock protein 90 inhibitor that enhances radiosensitization of MiaPaCa tumor cells.
| Keywords: | 17-Dimethyaminoethylamino-demethoxygeldanamycin |
| Application: | Hsp90 inhibitor |
| CAS | 467214-20-6 |
| MW: | 616,75 D |
From 116.00€
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17-DMAG
Item number: AG-CN2-0540-M001
Less toxic, more potent synthetic derivative of geldanamycin (Prod. No. BVT-0196). Angiogenesis inhibitor. Heat shock protein 90 (HSP90) inhibitor. Apoptosis inducer. Shows higher antitumor activity than 17-AAG (Prod. No. BVT-0244).
| CAS | 467214-20-6 |
From 39.00€
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Alvespimycin
Item number: TGM-T20890-100mg
Description: Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor that binds to Hsp90, exhibiting potential anticancer activity. Target: HSP. Smiles: CO[C@H]1C[C@H](C)CC2=C(NCCN(C)C)C(=O)C=C(NC(=O)\C(C)=C\C=C/[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)C2=O. References: Ge J, et al. Design, synthesis, and...
| Keywords: | KOS 1022, KOS-1022, KOS1022, 17-DMAG |
| CAS | 467214-20-6 |
| MW: | 616.75 D |
From 84.00€
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