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Item number: Cay36062-10

Maytansine is an ansa macrolide originally isolated from M. serrata that has anticancer activity. It inhibits the growth of L1210, L-5178-Y, and P388 murine leukemia cells (EC50s = 0.6, 12, and 1.5 nM, respectively). Maytansine (20 µM) inhibits erythrocyte and brain tubulin polymerization. In vivo, maytansine...

Keywords:	Maitansine, NSC 153858
Application:	Ansa macrolide, anticancer agent, beta-tubulin binding cytotoxic agent
CAS	35846-53-8
MW:	692.2 D

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Maytansine

Item number: TGM-T21351-10mg

Description: Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site. Target: Microtubule Associated, Antibiotic. Smiles:...

Keywords:	NSC153858, Maitansina, NSC-153858, Maitansine, NSC 153858
CAS	35846-53-8
MW:	692.2 D

From 56.00€ *

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