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BAY 57-1293
Item number: Cay22129-10
BAY-57-1293 is an orally bioavailable helicase-primase inhibitor. It inhibits the ATPase activity of herpes simplex virus (HSV) helicase-primase (IC50 = 30 nM). It inhibits HSV replication in Vero cells (IC50 = 20 nM for both HSV-1 and HSV-2) and is also active against porcine and bovine HSV strains (IC50s = 5 and...
| Keywords: | N-[5-(aminosulfonyl)-4-methyl-2-thiazolyl]-N-methyl-4-(2-pyridinyl)-benzeneacetamide |
| Application: | HSV helicase primase inhibitor |
| CAS | 348086-71-5 |
| MW: | 402.5 D |
From 53.00€
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Pritelivir
Item number: TGM-T2504-100mg
Description: Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM). Target: DNA/RNA Synthesis, HSV. Smiles: CN(C(=O)Cc1ccc(cc1)-c1ccccn1)c1nc(C)c(s1)S(N)(=O)=O. References: Kleymann G, et al. Nat Med. 2002, 8(4), 392-398.
| Keywords: | AIC316, BAY 57-1293 |
| Application: | Antiviral, Helicase-primase inhibitor |
| CAS | 348086-71-5 |
| MW: | 402.49 D |
From 30.00€
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