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N-Deacetylcolchicine
N-Deacetylcolchicine

Item number: Cay21697-1

N-Deacetylcolchicine is an inhibitor of tubulin polymerization (IC50 = 3 µM for bovine brain tubulin) and a derivative of the microtubule polymerization inhibitor colchicine (Cay-9000760). It stimulates tubulin GTPase activity.Formal Name: (7S)-7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-benzo[a]heptalen-9(5H)-one....
Keywords: NSC 201400, (7S)-7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-benzo[a]heptalen-9(5H)-one
Application: Tubulin polymerization inhibitor
CAS 3476-50-4
MW: 357.4 D
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N-Deacetylcolchicine
N-Deacetylcolchicine

Item number: TGM-T85194-10mg

Description: Trimethylcolchicinic acid methyl ether (HAN 76504), an antimitotic agent, blocks microtubule assembly by attaching to tubulin and inhibiting its polymerization. It enhances tubulin's intrinsic GTPase activity, induces apoptosis across various normal and tumor cell lines, and activates the JNK/SAPK...
Keywords: NSC 201400
Application: Tubulin polymerization inhibitor
CAS 3476-50-4
MW: 357.4 D
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Review