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C-178
C-178

Item number: LKT-C000078.100

C-178 is a STING inhibitor. SMILES: C1=CC=C2C(=C1)C3=C(O2)C=C(C=C3)NC(=O)C4=CC=C(O4)[N+](=O)[O-]
Keywords: C178, STING inhibitor C-178, 5-Nitro-furan-2-carboxylic acid dibenzofuran-3-ylamide,...
Application: STING inhibitor
CAS 329198-87-0
MW: 322.28 D
From 84.00€ *
Review
C-178
C-178

Item number: TGM-T7329-100mg

Description: C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells. Target: STING. Smiles: [O-][N+](=O)c1ccc(o1)C(=O)Nc1ccc2c(c1)oc1ccccc21. References: Haag S M , Gulen M F , Luc R , et al. Targeting STING...
Application: Covalent STING inhibitor
CAS 329198-87-0
MW: 322.27 D
From 38.00€ *
Review
C-178
C-178

Item number: Cay25860-10

C-178 is a covalent inhibitor of stimulator of interferon genes (STING). It binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells. C-178 (0.01-1.25 µM) selectively reduces STING-, but not RIG-I- or TBK1-, mediated IFN-beta reporter activity in...
Keywords: N-3-dibenzofuranyl-5-nitro-2-furancarboxamide
Application: Covalent STING inhibitor
CAS 329198-87-0
MW: 322.3 D
From 44.00€ *
Review