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MMG-11
MMG-11

Item number: TGM-T16123-2mg

Description: MMG-11 inhibits both TLR2/1 and TLR2/6 signaling (IC50s: 1.7 µM for Pam3CSK4-induced hTLR2/1 and 5.7 µM for Pam2CSK4-induced hTLR2/6 responses). MMG-11 is an effective and selective human TLR2 antagonist with low cytotoxicity. Target: Others. Smiles: CCOC(=O)c1ccc(CC(=O)c2ccc(O)c(O)c2O)o1. References:...
Application: TLR1/2 antagonist
CAS 313254-94-3
MW: 306.27 D
58.00€ *
Review
MMG-11
MMG-11

Item number: Cay38787-1

MMG-11 is an antagonist of the toll-like receptor 1/2 (TLR1/2) heterodimer (IC50 = 0.9 µM in HEK-Blue cells expressing the human receptors). It is selective for TLR1/2 over the TLR2/6 heterodimer (IC50 = 7.4 µM in HEK-Blue cells expressing the human receptors). MMG-11 inhibits TNF-alpha and IL-6 cytokine secretion...
Keywords: 5-[2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl]-2-furancarboxylic acid
Application: TLR1/2 antagonist
CAS 313254-94-3
MW: 306.3 D
From 36.00€ *
Review