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Simufilam Dihydrochloride
Simufilam Dihydrochloride

Item number: LKT-S336507.100

Simufilam was first introduced as having the potential to reduce biomarkers of Alzheimer's disease. The original data has since become suspect and could not be found. Fraud charges have been filed by the SEC. Simufilam may or may not have some useful bioactivities. The proper research, with proper data collection...
Keywords: PTI-125 dihydrochloride, PTI diHCl, JP8XRG9A58, 4-benzyl-8-methyl-1,4,8-triazaspiro[4.5]decan-3-one,dihydrochloride
Application: Unlikely to reverse Alzheimer's
CAS 2480226-06-8
MW: 332.3 D
From 229.00€ *
Review
PTI-125 (hydrochloride)
PTI-125 (hydrochloride)

Item number: Cay41859-10

PTI-125 is a purported binding agent of filamin A, a cytoskeletal protein said to stabilize the interaction between amyloid-beta (1-42) (Abeta42) and the alpha7 nicotinic acetylcholine receptor (nAChR). PTI-125 reportedly binds to filamin A to reverse an aberrant conformational change induced by Abeta42, which...
Keywords: 8-methyl-1-(phenylmethyl)-1,4,8-triazaspiro[4.5]decan-2-one, monohydrochloride
Application: Purported Filamin A binding agent
CAS 2480226-06-8
MW: 332.3 D
From 226.00€ *
Review
Simufilam dihydrochloride
Simufilam dihydrochloride

Item number: TGM-T9172-100mg

Description: Simufilam dihydrochloride (PTI-125 dihydrochloride) is a low toxicity, orally active filamin A (FLNA) activator, which can be used for the research of Alzheimer's disease. Simufilam dihydrochloride preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic...
Keywords: PTI-125 dihydrochloride
CAS 2480226-06-8
MW: 332.3 D
From 74.00€ *
Review