Simufilam dihydrochloride

Item number	Size	Delivery time	Price
TGM-T9172-1mg	1 mg	7 - 10 business days*	42.00€
TGM-T9172-5mg	5 mg	7 - 10 business days*	86.00€
TGM-T9172-1mL	1 ml	7 - 10 business days*	97.00€
TGM-T9172-10mg	10 mg	7 - 10 business days*	137.00€
TGM-T9172-25mg	25 mg	7 - 10 business days*	292.00€
TGM-T9172-50mg	50 mg	7 - 10 business days*	378.00€
TGM-T9172-100mg	100 mg	7 - 10 business days*	494.00€
TGM-T9172-200mg	200 mg	7 - 10 business days*	653.00€

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Description: Simufilam dihydrochloride (PTI-125 dihydrochloride) is a low toxicity, orally active... more

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Product information "Simufilam dihydrochloride"

Description: Simufilam dihydrochloride (PTI-125 dihydrochloride) is a low toxicity, orally active filamin A (FLNA) activator, which can be used for the research of Alzheimer's disease. Simufilam dihydrochloride preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its alpha7nAChR/TLR4 associations and downstream pathologies. Target: Others. Smiles: [H]Cl.O=C1N(CC2=CC=CC=C2)C3(CCN(C)CC3)NC1.[H]Cl. References: Wang HY, et al. PTI-125 binds and reverses an altered conformation of filamin A to reduce Alzheimer's disease pathogenesis. Neurobiol Aging. 2017,55:99-114.

Keywords:	PTI-125 dihydrochloride
Supplier:	TargetMol
Supplier-Nr:	T9172

Properties

MW:	332.3 D
Formula:	C15H23Cl2N3O

Database Information

CAS :

2480226-06-8| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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