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Item number: Cay19643-1

L-748,337 is a beta3-adrenergic receptor antagonist that displays selectivity over beta1 and beta2 receptors (Kis = 4, 390, and 204 nM, respectively). It has been shown to couple with Gi to activate MAPK signaling. L-748,337 can inhibit agonist-stimulated lipolysis in rhesus monkey adipocytes, as well as...

Keywords:	N-[[3-[(2S)-2-hydroxy-3-[[2-[4-[(phenylsulfonyl)amino]phenyl]ethyl]amino]propoxy]phenyl]methyl]-acetamide
Application:	beta3-adrenoceptor antagonist
CAS	244192-94-7
MW:	497.6 D

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L748337

Item number: TGM-T22905-1mg

Description: L748337 is a competitive and potent beta3-adrenoceptor antagonist that inhibits the action of beta3-, beta2-, and beta1-adrenoceptors, activates MAPK signaling, promotes phosphorylation of Erk1/2, and inhibits the protective effects of CL316243, and is used in the study of disorders caused by...

Keywords:	L-748,337
Application:	beta3-adrenoceptor antagonist
CAS	244192-94-7
MW:	497.61 D

59.00€ *

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