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Clozapine N-oxide (hydrochloride)
Clozapine N-oxide (hydrochloride)

Item number: Cay25780-25

Clozapine N-oxide is a major metabolite of clozapine (Cay-12059) and an activator of designer receptors exclusively activated by designer drugs (DREADDs) derived from human muscarinic acetylcholine receptors (EC50s = 16.7, 323, 17.4, 18.3, and 18.7 nM for PASMCs expressing hM1-5D receptors, respectively). It...
Keywords: CNO, 8-chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine, dihydrochloride
Application: DREADD / RASSL activator
CAS 2250025-93-3
MW: 415.7 D
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