Benfotiamine is a lipid-soluble form of vitamin B1 (thiamine). In vitro, it corrects defective replication of, and prevents formation of advanced glycosylation end products (AGEs) in, human umbilical vein endothelial cells (HUVECs) grown under high glucose conditions. In vivo, administration of benfotiamine...

A lipid-soluble thiamine derivative found in Allium family vegetables such as garlic, onions, leeks and shallots. As a treatment for diabetic neuropathy, benfotiamine is more effective at increasing thiamine levels in blood and tissues than water-soluble salts like the previous vitamin B1.

S-Benzoylthiamine O-monophosphate is a lipid-soluble form of vitamin B1 (thiamine). S-Benzoylthiamine O-monophosphate facilitates the action of thiamine diphosphate, a cofactor for the enzyme transketolase. The activation of transketolase enzyme accelerates the precursors of advanced glycation end products (AGEs)...