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CHMFL-FLT3-122
CHMFL-FLT3-122

Item number: Cay43137-1

CHMFL-FLT3-122 is an inhibitor of FMS-related tyrosine kinase 3 (FLT3, IC50 = 40 nM). It is selective for FLT3 over Bruton's tyrosine kinase (BTK) and C-Kit (IC50s = 421 and 559 nM, respectively) and a panel of 468 additional kinases at 1 µM. CHMFL-FLT3-122 inhibits the growth of MV4-11, MOLM-13, and MOLM-14 acute...
Keywords: HYML-122, 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-(dimethylamino)-ethanone
Application: FMS-related tyrosine kinase 3 (FLT3) inhibitor
CAS 1839150-56-9
MW: 471.57 D
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