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Item number: TGM-TQ0033-100mg

Description: Zegocractin (CM-4620) is an inhibitor of calcium-release activated calcium (CRAC) channels. Target: Calcium Channel. Smiles: Cc1cccc(F)c1C(=O)Nc1cnc(cn1)-c1cc2OC(F)(F)Oc2cc1Cl. References: ARYL SULFONOHYDRAZIDES. WO2016/138472Al.

Keywords:	CM4620, N-(5-(6-Chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide, CM-4620
CAS	1713240-67-5
MW:	421.76 D

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CM-4620

Item number: Cay41977-10

An inhibitor of Orai1/STIM1-containing SOCs (IC50 = 120 nM), selective for Orai1/STIM1-containing SOCs over Orai2/STIM2-containing SOCs (IC50 = 900 nM), decreases cholecystokinin- or taurolithocholic acid 3-sulfate-induced cell death in isolated mouse, rat, and human acini at 3 µM, reduces blood amylase and lipase...

Keywords:	Zegrocractin, N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)-2-pyrazinyl]-2-fluoro-6-methyl-benzamide
Application:	Orai1/STIM1-containing SOC (store-operated calcium channel) inhibitor
CAS	1713240-67-5
MW:	421.8 D

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