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Deruxtecan
Item number: BPS-84320-1
Deruxtecan is a linker-payload conjugate made of a derivative of DX-8951 and the maleimide-GGFC peptide linker. It is used to synthetize ADCs (antibody drug conjugates), such as trastuzumab deruxtecan and patritumab deruxtecan. ADC (antibody drug conjugates) are a promising therapeutic strategy. ADCs are composed of...
| Application: | ADC (antibody drug conjugate) preparation |
| CAS | 1599440-13-7 |
| MW: | 1034.05 D |
From 614.00€
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Deruxtecan
Item number: Cay43189-10
A reactive drug-linker molecule containing Dxd, has been linked trastuzumab as an ADC to target Dxd to tumor cells, binds to HER2 in a cell-free assay, is cytotoxic to breast cancer cells in vitro, and induces tumor regression in a BT474 breast cancer mouse xenograft model. when linked to trastuzumab. Formulation: A...
| Keywords: | Maleimidocaproyl-Gly-Gly-Phe-Gly-Dxd, Mc-GGFG-Dxd,... |
| Application: | Reactive drug-linker molecule, ADC |
| CAS | 1599440-13-7 |
| MW: | 1034.07 D |
From 76.00€
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Deruxtecan
Item number: TGM-T15098-10mg
Description: Deruxtecan is an ADC drug-linker conjugate comprising a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used in synthesizing DS-8201 and U3-1402. Target: Others, Drug-Linker Conjugates for ADC. Smiles:...
| CAS | 1599440-13-7 |
| MW: | 1034.05 D |
From 131.00€
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