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Item number: Cay43189-10

A reactive drug-linker molecule containing Dxd, has been linked trastuzumab as an ADC to target Dxd to tumor cells, binds to HER2 in a cell-free assay, is cytotoxic to breast cancer cells in vitro, and induces tumor regression in a BT474 breast cancer mouse xenograft model. when linked to trastuzumab. Formulation: A...

Keywords:	Maleimidocaproyl-Gly-Gly-Phe-Gly-Dxd, Mc-GGFG-Dxd,...
Application:	Reactive drug-linker molecule, ADC
CAS	1599440-13-7
MW:	1034.07 D

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Deruxtecan

Item number: TGM-T15098-10mg

Description: Deruxtecan is an ADC drug-linker conjugate comprising a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used in synthesizing DS-8201 and U3-1402. Target: Others, Drug-Linker Conjugates for ADC. Smiles:...

CAS	1599440-13-7
MW:	1034.05 D

From 131.00€ *

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