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L-161,982
Item number: Cay10011565-1
Prostaglandin E2 (PGE2) exerts its effects through four separate G coupled-protein receptors (EP1-4). L-161,982 is a potent and selective EP4 receptor antagonist. It demonstrates selective binding to human EP4 receptors with a Ki value of 0.024 µM compared to other receptors of the prostanoid family, EP1, EP2, EP3,...
| Keywords: | N-[[4'-[[3-butyl-1,5-dihydro-5-oxo-1-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl]methyl][1,1'-biphenyl]-2-yl]sulfony... |
| Application: | EP4 receptor antagonist |
| CAS | 147776-06-5 |
| MW: | 654.7 D |
From 52.00€
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L-161982
Item number: TGM-T15681-100mg
Description: L-161982 is a selective antagonist of EP4 receptor. L-161982 could inhibit PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. L-161982 could alleviate collagen-induced arthritis in mice. Target: Prostaglandin Receptor. Smiles:...
| Application: | EP4 receptor antagonist |
| CAS | 147776-06-5 |
| MW: | 654.72 D |
From 72.00€
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