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Item number: Cay18612-10

Amifostine thiol is a radioprotective agent and an active metabolite of amifostine (Cay-14398). It is formed from amifostine by plasma membrane-bound alkaline phosphatase. Amifostine thiol scavenges ABTS (Cay-27317) radicals in a cell-free assay. It prevents single- and double-stranded DNA breaks induced by...

Keywords:	WR 1065, 2-[(3-aminopropyl)amino]-ethanethiol, dihydrochloride
Application:	Radioprotective agent
CAS	14653-77-1
MW:	207.2 D

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Amifostine thiol dihydrochloride

Item number: TGM-TQ0133-10mg

Description: Amifostine thiol dihydrochloride (WR 1065) can activate p53 through a JNK-dependent signaling pathway. It also protects normal tissues from the toxic effects of certain cancer drugs. Target: p53. Smiles: Cl.Cl.NCCCNCCS. References: Pluquet O, et al. The cytoprotective aminothiol WR1065 activates p53...

Keywords:	WR 1065
CAS	14653-77-1
MW:	207.165 D

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