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Item number: TGM-T15590-10mg

Description: Iodophenpropit dihydrobromide is an effective and selective antagonist of the histamine H3 receptor. The binding of [125I]Iodophenpropit is readily reversible, selective, and of high affinity (KD: 0.32 nM). Target: Histamine Receptor. Smiles: Br.Ic1ccc(CCNC(=N)SCCCc2cnc[nH]2)cc1. References: Jansen FP,...

Application:	Histamine H3 receptor antagonist
CAS	145196-87-8
MW:	495.22 D

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Iodophenpropit (hydrobromide)

Item number: Cay32850-1

Iodophenpropit is a histamine H3 receptor antagonist (pA2 = 9.6 in guinea pig intestine, which has a high endogenous expression of H3 receptors). It increases forskolin-induced cAMP production in SK-N-MC cells expressing the recombinant human H3 receptor (EC50 = 25.1 nM). It is also an inhibitor of NR1/NR2A,...

Keywords:	[2-(4-iodophenyl)ethyl]-carbamimidothioic acid, 3-(1H-imidazol-4-yl)propyl ester, dihydrobromide
Application:	Histamine H3 receptor antagonist
CAS	145196-87-8
MW:	576.1 D

From 62.00€ *

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