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Item number: Cay20992-10

AM2394 is an activator of glucokinase with an EC50 value of 60 nM in an enzyme assay in the presence of glucose. Oral administration of AM2394 (3-30 mg/kg) decreases plasma glucose levels in an oral glucose tolerance test in an ob/ob mouse model of diabetes.Formal Name:...

Keywords:	N-[6'-(2-hydroxy-2-methylpropoxy)-4-[(5-methyl-3-pyridinyl)oxy][3,3'-bipyridin]-6-yl]-N'-methyl-urea
Application:	Glucokinase agonist
CAS	1442684-77-6
MW:	423.5 D

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AM-2394

Item number: TGM-T3312-100mg

Description: AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-2394(AM2394) increases the affinity of GK for glucose by approximately 10-fold, exhibits moderate clearance and good oral bioavailability in multiple...

Keywords:	AM2394
Application:	Glucokinase agonist
CAS	1442684-77-6
MW:	423.46 D

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