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CAY10574
CAY10574

Item number: Cay10011247-5

Cyclin-dependent kinases (CDKs) play a key role in regulating cell division by phosphorylating distinct substrates in different phases of the cell cycle. Cell cycle deregulation in many cancers often results from altered CDK activity. Thus, CDKs are potential pharmacological targets for anticancer agents. CAY10574...
Keywords: 4-[(3,5-diamino-1H-pyrazol-4-yl)azo]-phenol
Application: CDK9 inhibitor
CAS 140651-18-9
MW: 218.2 D
From 38.00€ *
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CAN508
CAN508

Item number: TGM-T8796-100mg

Description: CAN508 is a potent ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 µM. It also competitively inhibits Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 µM and 20 µM, respectively. CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes....
Application: CDK9 inhibitor
CAS 140651-18-9
MW: 218.22 D
From 30.00€ *
Review