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Bisindolylmaleimide VIII (acetate)
Item number: Cay13333-1
Bisindolylmaleimide VIII (BIM VIII) is a selective protein kinase C (PKC) inhibitor (IC50 = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. This compound exhibits some degree of PKC isozyme specificity with preference for PKCalpha over PKCbetaI, PKCbetaII, PKCgamma, or PKCepsilon (IC50s = 53,...
| Keywords: | BIM VIII, Ro 31-7549, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione, acetate |
| Application: | PKC inhibitor |
| CAS | 138516-31-1 |
| MW: | 458.5 D |
From 68.00€
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Bisindolylmaleimide VIII-AcOH
Item number: AG-CR1-0114-M001
Selective protein kinase C (PKC) inhibitor. Inhibits proliferation of cultured mouse epidermal keratinocytes. Enhances Fas- and TRAIL-mediated apoptosis. Inhibits T cell-mediated autoimmune diseases. Inhibits stimulation of insulin secretion by glucose. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2).
| Keywords: | Ro 31-7549, BIM VIII |
| Application: | PKC inhibitor |
| CAS | 138516-31-1 |
From 55.00€
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