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Item number: TGM-T38068-2mg

Description: Potent and noncompetitive NMDA receptor antagonist (IC50 = 36 nM). Exhibits >70-fold selectivity for NMDA receptor over sigma receptor. Neuroprotective in a rat model of focal ischemia. Target: Others. Smiles: Cl.CCc1cccc(c1)N(C)C(=N)Nc1cccc2ccccc12. References: Reddy et al (1994) Synthesis and...

Application:	Stroke treatment, NMDA receptor antagonist
CAS	137160-11-3
MW:	339.87 D

81.00€ *

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Cerestat

Item number: Cay30966-1

Cerestat is an NMDA receptor antagonist (IC50 = 36 nM). It is selective for the NMDA receptor over sigma receptors (IC50 = 2,540 nM). Cerestat (1 mg/kg) reduces infarct volume and the number of steps and errors in a foot fault test in a rat model of stroke induced by middle cerebral artery occlusion. It also reduces...

Keywords:	CNS 1102, N-(3-ethylphenyl)-N-methyl-N'-1-naphthalenyl-guanidine, monohydrochloride
Application:	NMDA receptor antagonist
CAS	137160-11-3
MW:	339.9 D

From 85.00€ *

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