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Flavopiridol hydrochloride
Item number: TGM-T2615-10mg
Description: Flavopiridol hydrochloride (MDL 107826A) is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression,...
| Keywords: | MDL 107826A, Alvocidib Hydrochloride, NSC 649890, NSC 649890 HCl, HL 275, FLAVOPIRIDOL HCL |
| Application: | Targets cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23] (CDK1, CDC2) |
| CAS | 131740-09-5 |
| MW: | 438.3 D |
From 45.00€
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Flavopiridol (hydrochloride)
Item number: Cay10009197-5
Flavopiridol is an orally bioavailable inhibitor of cyclin dependent kinases (IC50s = ~100, ~100, ~100, and 300 nM for Cdk1, Cdk2, Cdk4, and Cdk7, respectively). It also inhibits TEFb, a complex composed of Cdk9 and cyclin T1, with a Ki value of 3 nM. Flavopiridol inhibits transcription of a CMV promoter in HeLa...
| Keywords: | Alvocidib, HL 275, HMR 1275, L-868,275,... |
| CAS | 131740-09-5 |
| MW: | 438.3 D |
From 67.00€
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Flavopiridol Hydrochloride
Item number: LKT-F441026.25
| Keywords: | Flavopiridol HCl, Alvocidib hydrochloride, Alvocidib HCl |
| Application: | CDK inhibitor |
| CAS | 131740-09-5 |
| MW: | 438.3 D |
From 185.00€
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