Flavopiridol hydrochloride
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Flavopiridol hydrochloride (MDL 107826A) is a synthetic N-methylpiperidinyl... more
Product information "Flavopiridol hydrochloride"
Description: Flavopiridol hydrochloride (MDL 107826A) is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity. Target: Autophagy, CDK, HIV Protease. Smiles: Cl.CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl. References: Senderowicz AM, Oncologist, 2002, 7 Suppl 3:12-9.
| Keywords: | MDL 107826A, Alvocidib Hydrochloride, NSC 649890, NSC 649890 HCl, HL 275, FLAVOPIRIDOL HCL |
| Supplier: | TargetMol |
| Supplier-Nr: | T2615 |
Properties
| Application: | Targets cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23] (CDK1, CDC2) |
| MW: | 438.3 D |
| Formula: | C21H21Cl2NO5 |
Database Information
| CAS : | 131740-09-5| Matching products |
| KEGG ID : | K02087 | Matching products |
| Protein Atlas Nr. : | Apoptosis, Cell Cycle, DNA Repair |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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