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Item number: TGM-T71965-5mg

Description: KRIBB3 is novel and potent microtubule inhibitor with potential anticancer activity. KRIBB3 has anti-migratory and anti-invasive activities in MDA-MB-231 cells. KRIBB3 inhibits tumor cell migration and invasion by blocking protein kinase C-dependent phosphorylation of Hsp27 through its direct binding to...

Application:	Hsp27 inhibitor, microtubule inhibitor
CAS	129414-88-6
MW:	325.36 D

829.00€ *

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KRIBB3

Item number: Cay23973-5

KRIBB3 is an Hsp27 and microtubule inhibitor that inhibits migration and invasion of MDA-MB-231 cells in vitro in an Hsp27-dependent manner. It inhibits protein kinase C (PKC) phosphorylation of Hsp27 but not phospholipase Cbeta3, indicating KRIBB3 interaction with Hsp27 is preventing its phosphorylation. KRIBB3...

Keywords:	4-ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]-phenol
Application:	Hsp27 inhibitor, microtubule inhibitor
CAS	129414-88-6
MW:	325.4 D

454.00€ *

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